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'''OR1A1''' is a gene that encodes the olfactory receptor 1A1 protein in humans. The [[olfactory receptor]] family is believed to be the largest gene family in the human genome. These receptors are responsible for the detection of odor molecules, playing a crucial role in the sense of [[smell (olfaction)|smell]].

== Function ==

The OR1A1 gene belongs to the [[olfactory receptor genes|olfactory receptor gene family]], which is a part of the G protein-coupled receptor superfamily. The olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response, resulting in the perception of a smell. The OR1A1 gene provides instructions for making a protein that is located in the membranes of cells in the nose. This protein detects certain odor molecules and sends signals to the brain, providing the sense of smell.

== Structure ==

The OR1A1 gene is located on the short (p) arm of [[chromosome 11]] at position 15. The exact location is 11p15.4, from base pair 3,000,000 to base pair 3,100,000. The gene spans approximately 1,000 base pairs. The OR1A1 gene produces a protein that is 312 amino acids long.

== Clinical significance ==

Mutations in the OR1A1 gene can lead to a reduced ability to smell, a condition known as [[anosmia]]. In some cases, mutations can cause a complete loss of smell. Research is ongoing to determine the full range of conditions that can be caused by mutations in this gene.

== See also ==
* [[Olfactory receptor]]
* [[Olfactory system]]
* [[Anosmia]]
* [[Chromosome 11]]

== References ==
<references />

[[Category:Genes]]
[[Category:Olfactory system]]
[[Category:Human proteins]]

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OR1A1 - Revision history

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