https://wikimd.com/index.php?action=history&feed=atom&title=OPN5OPN5 - Revision history2026-04-24T13:12:04ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.com/index.php?title=OPN5&diff=6316410&oldid=prevPrab: CSV import2025-02-18T04:15:49Z<p>CSV import</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:15, 18 February 2025</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l22">Line 22:</td>
<td colspan="2" class="diff-lineno">Line 22:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Visual system]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Visual system]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><gallery></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:CC-BY_icon.svg|OPN5</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Opsin_Phylogeny_with_the_main_Groups_the_Tetraopsins_Highlighted.svg|Opsin Phylogeny with the main Groups, the Tetraopsins Highlighted</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Tetraopsin_Phylogeny_with_the_Neuropsins_Highlighted.svg|Tetraopsin Phylogeny with the Neuropsins Highlighted</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></gallery></ins></div></td></tr>
</table>Prabhttps://wikimd.com/index.php?title=OPN5&diff=5380391&oldid=prevPrab: CSV import2024-03-10T07:33:11Z<p>CSV import</p>
<p><b>New page</b></p><div>'''OPN5''' is a [[protein]] that in humans is encoded by the OPN5 [[gene]]. OPN5 is a member of the [[opsin]] family of proteins, which are integral components of the [[visual system]] in most organisms. <br />
<br />
== Function ==<br />
OPN5 is a UV-sensitive opsin, also known as neuropsin. It is expressed in the [[retina]] and brain, and is involved in the regulation of [[circadian rhythms]]. OPN5 is a bistable opsin, meaning it can exist in two stable states, and can be switched between these states by light. This property allows it to function as a [[photoreceptor]], detecting light and transmitting this information to the brain.<br />
<br />
== Structure ==<br />
Like other opsins, OPN5 is a [[G protein-coupled receptor]] (GPCR). It consists of seven transmembrane domains, with the chromophore retinal covalently attached to a lysine residue in the seventh domain. The structure of OPN5 is highly conserved across species, suggesting it plays a crucial role in the visual system.<br />
<br />
== Clinical significance ==<br />
Mutations in the OPN5 gene have been associated with certain [[eye disorders]], including [[night blindness]] and certain forms of [[color blindness]]. However, more research is needed to fully understand the role of OPN5 in these conditions.<br />
<br />
== See also ==<br />
* [[Opsin]]<br />
* [[Photoreceptor cell]]<br />
* [[Visual system]]<br />
<br />
== References ==<br />
<references /><br />
<br />
[[Category:G protein-coupled receptors]]<br />
[[Category:Human proteins]]<br />
[[Category:Visual system]]<br />
{{medicine-stub}}</div>Prab