https://wikimd.org/index.php?action=history&feed=atom&title=Nystatin_TopicalNystatin Topical - Revision history2026-04-27T19:53:30ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Nystatin_Topical&diff=4519626&oldid=prevDeepika vegiraju at 14:50, 2 November 20222022-11-02T14:50:21Z<p></p>
<p><b>New page</b></p><div>== '''What is Nystatin Topical?'''==<br />
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* Nystatin Topical is '''a polyene antifungal antibiotic''' obtained from [[Streptomyces noursei]] used to treat fungal infections of the skin. <br />
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[[File:Nystatin.svg|thumb|Nystatin]]<br />
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[[File:Nystatin ball-and-stick.png|thumb|Nystatin ball-and-stick]]<br />
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[[File:Nystatin.png|thumb|Nystatin]]<br />
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== '''What are the uses of this medicine?''' ==<br />
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* Nystatin Topical is used in the treatment of [[cutaneous]] or [[mucocutaneous]] [[Mycotic|mycotic infections]] caused by [[Candida albicans]] and other susceptible [[Candida (fungus)|Candida species]].<br />
* Nystatin Cream USP is not indicated for systemic, oral, [[intravaginal]] or [[ophthalmic]] use.<br />
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== '''How does this medicine work?''' ==<br />
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* Nystatin is an antibiotic which is both '''[[Fungistatics|fungistatic]] and [[fungicidal]]''' in vitro against a wide variety of yeasts and yeast-like fungi, including [[Candida albicans]], [[Candida parapsilosis|C. parapsilosis]], [[C. tropicalis]], [[C. guilliermondi]], [[C. pseudotropicalis]], [[Candida krusei|C. krusei]], [[Torulopsis glabrata]], [[Tricophyton rubrum]], [[T. mentagrophytes]].<br />
* Nystatin '''acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components'''. <br />
* Nystatin exhibits no appreciable activity against bacteria, [[protozoa]], or viruses.<br />
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== '''Who Should Not Use this medicine ?''' ==<br />
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This medicine cannot be used in patients with:<br />
* with a history of [[hypersensitivity]] to any of its components.<br />
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== '''What drug interactions can this medicine cause?''' ==<br />
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* Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.<br />
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== '''Is this medicine FDA approved?''' ==<br />
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* Nystatin was approved by the FDA in 1971 and is currently widely used in the treatment of superficial yeast infections and [[Candida infection|candida infections]] of the skin, [[mucous membranes]] and [[gastrointestinal tract]], including [[oropharyngeal candidiasis]].<br />
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== '''How should this medicine be used?''' ==<br />
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'''Recommended dosage:'''<br />
'''Adults and Pediatric Patients (Neonates and Older):'''<br />
* Apply liberally to affected areas twice daily or as indicated until healing is complete.<br />
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'''Administration:'''<br />
* Nystatin comes as a cream, ointment and powder to apply to the skin. <br />
* Nystatin cream and ointment is usually applied twice a day to the affected area. Nystatin powder is usually used two or three times a day. <br />
* Use nystatin at around the same times every day. <br />
* If you are using powder for infected feet, dust the powder inside your shoes and stockings as well as on your feet.<br />
* Topical nystatin is only for use on the skin. <br />
* Do not let nystatin get into your vagina, eyes, or mouth, and do not swallow the medication.<br />
* Use nystatin as long as instructed by your doctor, even if you feel better. If you stop using nystatin too soon or skip doses, your infection may not be completely treated.<br />
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== '''What are the dosage forms and brand names of this medicine?''' ==<br />
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This medicine is available in fallowing doasage form:<br />
* As Nystatin Cream USP for topical use, contains 100,000 USP nystatin units per gram. <br />
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This medicine is available in fallowing brand namesː<br />
* '''Barstatin Powder'''<br />
* '''Candex Cream'''<br />
* '''Mycostatin Cream'''<br />
* '''Mycostatin Ointment'''<br />
* '''Mycostatin Powder'''<br />
* '''Mykinac Cream'''<br />
* '''Mykinac Ointment'''<br />
* '''Nilstat Cream'''<br />
* '''Nilstat Ointment'''<br />
* '''Nilstat Powder'''<br />
* '''Nyamyc Powder'''<br />
* '''Nystop Powder'''<br />
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=='''What side effects can this medication cause?'''==<br />
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The most common side effects of this medicine include:<br />
* allergic reactions <br />
* burning <br />
* itching <br />
* [[rash]] <br />
* [[eczema]] <br />
* pain on application <br />
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==''' What special precautions should I follow?''' ==<br />
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* Nystatin Cream USP should not be used for the treatment of systemic, oral, [[intravaginal]] or [[ophthalmic]] infections.<br />
* Even if symptomatic relief occurs within the first few days of treatment, the patient should be advised not to interrupt or discontinue therapy until the prescribed course of treatment is completed.<br />
* If symptoms of irritation develop, the patient should be advised to notify the physician promptly.<br />
* It is not known whether Nystatin is excreted in human milk. Caution should be exercised when nystatin is prescribed for a nursing woman.<br />
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== '''What to do in case of emergency/overdose?''' ==<br />
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* {{overdose}}<br />
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== '''Can this medicine be used in pregnancy?''' ==<br />
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* Category C.<br />
* It is not known whether these preparations can cause fetal harm when used by a pregnant woman or can affect reproductive capacity. <br />
* Nystatin topical preparations should be prescribed for a pregnant woman only if the potential benefit to the mother outweighs the potential risk to the fetus.<br />
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=='''Can this medicine be used in children?'''==<br />
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* Safety and effectiveness have been established in the pediatric population from birth to 16 years.<br />
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== '''What are the active and inactive ingredients in this medicine?''' ==<br />
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'''Active ingredient:'''<br />
* Nystatin<br />
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'''Inactive ingredients:'''<br />
* emulsifying wax, glycerin, isopropyl myristate, lactic acid, purified water, sodium hydroxide, and sorbic acid.<br />
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== '''Who manufactures and distributes this medicine?''' ==<br />
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'''Manufactured By:''' <br />
* [[Perrigo]]<br />
* Bronx, NY <br />
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'''Distributed By:'''<br />
* Perrigo<br />
* Allegan, MI<br />
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== '''What should I know about storage and disposal of this medication?''' ==<br />
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* Store at 20-25°C (68-77°F).<br />
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{{Antidiarrheals, intestinal anti-inflammatory/anti-infective agents}}<br />
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[[Category:Antifungals]]<br />
[[Category:Polyketides]]<br />
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[[Category:Vicinal diols]]<br />
[[Category:Secondary alcohols]]<br />
[[Category:Amines]]<br />
[[Category:Carboxylic acids]]<br />
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[[Category:Acetals]]</div>Deepika vegiraju