https://wikimd.org/index.php?action=history&feed=atom&title=NicomorphineNicomorphine - Revision history2026-04-25T04:48:42ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Nicomorphine&diff=6306202&oldid=prevPrab: CSV import2025-02-17T01:55:30Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Nicomorphine''' (also known as '''3,6-dinicotinoylmorphine''') is a powerful [[opioid]] analgesic drug, which is an [[opioid ester]] derivative of [[morphine]]. It was invented in 1904 in Vienna, Austria by the pharmacist Heinrich E. Merck and was marketed by the Merck company of Darmstadt, Germany under the brand name '''Alodyn'''.<br />
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==Pharmacology==<br />
Nicomorphine is metabolised in the body into [[morphine]] and [[nicotinic acid]]. The drug is approximately between half and a full time as potent as [[morphine]] by weight. This means that a dose of about 120 mg of nicomorphine will have the same analgesic effect as 60–100 mg of morphine if given intravenously.<br />
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==Medical uses==<br />
Nicomorphine is used for pain relief in a manner similar to morphine, but it is not used as a substitute for morphine in the treatment of addiction. It is used in many countries where it is available for prescription under various brand names, including Alodyn, Nicomorfin, and Vilan.<br />
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==Side effects==<br />
The side effects of nicomorphine are similar to those of other opioids and include [[itching]], [[nausea]], [[vomiting]], [[drowsiness]], and [[respiratory depression]].<br />
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==Legal status==<br />
Nicomorphine is a Schedule I controlled substance in the United States, meaning it has a high potential for abuse and no accepted medical use. In other countries, it is controlled under similar laws to those governing morphine.<br />
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==See also==<br />
* [[List of opioids]]<br />
* [[Opioid epidemic]]<br />
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[[Category:Opioids]]<br />
[[Category:Drugs]]<br />
[[Category:Pharmacology]]<br />
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