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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Neovascularization</id>
	<title>Neovascularization - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Neovascularization"/>
	<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Neovascularization&amp;action=history"/>
	<updated>2026-05-12T16:04:17Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=Neovascularization&amp;diff=6525223&amp;oldid=prev</id>
		<title>Prab at 13:00, 18 March 2025</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Neovascularization&amp;diff=6525223&amp;oldid=prev"/>
		<updated>2025-03-18T13:00:18Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 13:00, 18 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Neovascularization&amp;diff=6514809&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Neovascularization&amp;diff=6514809&amp;oldid=prev"/>
		<updated>2025-03-17T20:15:13Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 20:15, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Neovascularization&amp;diff=6275466&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Neovascularization&amp;diff=6275466&amp;oldid=prev"/>
		<updated>2025-02-11T04:23:37Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 04:23, 11 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l32&quot;&gt;Line 32:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Neovascularization&amp;diff=5240720&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Neovascularization&amp;diff=5240720&amp;oldid=prev"/>
		<updated>2024-02-23T11:12:04Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Neovascularization&amp;#039;&amp;#039;&amp;#039; is the natural process in the body where new [[blood vessels]] are formed from pre-existing vessels. This process is crucial in the body&amp;#039;s normal growth and development, as well as in wound healing and the formation of [[granulation tissue]]. However, it is also a fundamental step in the transition of tumors from a benign state to a malignant one, leading to the use of [[angiogenesis inhibitors]] in the treatment of [[cancer]].&lt;br /&gt;
&lt;br /&gt;
==Mechanism==&lt;br /&gt;
Neovascularization is regulated by chemical signals in the body. These signals may be either pro-angiogenic signals, which stimulate the growth of new vessels, or anti-angiogenic signals, which inhibit the growth. The process of neovascularization is considered to occur in several stages, including [[vasodilation]], [[endothelial cell]] migration, proliferation, and tube formation.&lt;br /&gt;
&lt;br /&gt;
==Types==&lt;br /&gt;
There are two types of neovascularization: physiological and pathological. &lt;br /&gt;
&lt;br /&gt;
===Physiological===&lt;br /&gt;
Physiological neovascularization is a normal process that occurs in the body. It is essential for the body&amp;#039;s growth and development, and for wound healing. It is also involved in the menstrual cycle and in the formation of the placenta during pregnancy.&lt;br /&gt;
&lt;br /&gt;
===Pathological===&lt;br /&gt;
Pathological neovascularization, on the other hand, is abnormal and can lead to a number of diseases. It is a fundamental step in the transition of tumors from a benign state to a malignant one, and is therefore a target for cancer treatment. It can also occur in the eye, leading to conditions such as [[diabetic retinopathy]] and [[age-related macular degeneration]].&lt;br /&gt;
&lt;br /&gt;
==Clinical significance==&lt;br /&gt;
Neovascularization plays a crucial role in the growth and spread of cancer. Tumors stimulate the growth of new blood vessels because they need a blood supply to grow. This process is called tumor angiogenesis. Inhibiting angiogenesis is a potential way to prevent the growth and spread of cancer.&lt;br /&gt;
&lt;br /&gt;
Neovascularization is also involved in a number of eye diseases, including diabetic retinopathy and age-related macular degeneration. In these conditions, abnormal blood vessels grow in the retina, which can lead to vision loss.&lt;br /&gt;
&lt;br /&gt;
==See also==&lt;br /&gt;
* [[Angiogenesis]]&lt;br /&gt;
* [[Vasculogenesis]]&lt;br /&gt;
* [[Cancer]]&lt;br /&gt;
* [[Diabetic retinopathy]]&lt;br /&gt;
* [[Age-related macular degeneration]]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Angiogenesis]]&lt;br /&gt;
[[Category:Oncology]]&lt;br /&gt;
[[Category:Ophthalmology]]&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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