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2025-02-18T00:42:03Z

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← Older revision		Revision as of 00:42, 18 February 2025
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			<gallery>
			File:Nelfinavir_structure.svg\|Chemical structure of Nelfinavir
			File:Nelfinavir_ball-and-stick.png\|Ball-and-stick model of Nelfinavir
			File:Neutroncrosssectionboron.png\|Neutron cross-section of Boron
			</gallery>

Prab: Created page with " {{intro}} Nelfinavir is an antiretroviral protease inhibitor used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodef..."

2019-05-01T14:06:12Z

Created page with " {{intro}} Nelfinavir is an antiretroviral protease inhibitor used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodef..."

New page

{{intro}}
Nelfinavir is an antiretroviral protease inhibitor used in the therapy and prevention of human immunodeficiency virus ([[HIV]]) infection and the acquired immunodeficiency syndrome ([[AIDS]]).

{{livtox}}
Nelfinavir can cause transient and usually asymptomatic elevations in serum [[aminotransferase]] levels and is a rare cause of clinically apparent, acute [[liver injury]]. In HBV or HCV coinfected patients, hepatic injury during antiretroviral therapy that includes nelfinavir may be a result of exacerbation of the underlying chronic hepatitis B or C, rather than a direct effect of the medication.

{{moa}}
Nelfinavir (nel fin' a vir) is a nonpeptidic protease inhibitor that acts by binding to the catalytic site of the [[HIV]] protease, thereby preventing the cleavage of viral polyprotein precursors into mature, functional proteins that are necessary for viral replication.

{{PAGENAME}} was approved for use in the United States in 1997 for the therapy of [[HIV]] infection in both adults and children. Nelfinavir is available in tablets of 250 and 625 mg and as an oral suspension powder under the brand name Viracept.

{{dose}}
The recommended dosage of nelfinavir for adults is 1250 mg twice or 750 mg three times daily.

{{se}}
Common side effects include [[nausea]], [[diarrhea]], [[gastrointestinal upset]], fatigue and, with long term use, hyperlipidemia and lipodystrophy.
{{antiviral agents}}
{{coststubd}}

Nelfinavir - Revision history

Prab: CSV import

Prab: Created page with " {{intro}} Nelfinavir is an antiretroviral protease inhibitor used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodef..."