https://wikimd.org/index.php?action=history&feed=atom&title=Nedaplatin 2026-04-25T20:54:15Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Nedaplatin&diff=5368965&oldid=prev 2024-03-06T04:40:53Z

<p>CSV import</p> <p><b>New page</b></p><div>[[File:Nedaplatin.png|thumb|{{PAGENAME}}]]&lt;br&gt;&#039;&#039;&#039;Nedaplatin&#039;&#039;&#039; is a [[platinum]]-based [[chemotherapy]] drug used in the treatment of various types of [[cancer]], including [[lung cancer]], [[esophageal cancer]], and [[cervical cancer]]. It is a second-generation platinum compound with a similar mechanism of action to [[cisplatin]], but with less [[toxicity]] and fewer side effects.<br /> <br /> == History ==<br /> <br /> Nedaplatin was developed by [[Shionogi]] in Japan and was first approved for use in 1995. It was designed to overcome the limitations of cisplatin, particularly its high toxicity and resistance. <br /> <br /> == Mechanism of Action ==<br /> <br /> Nedaplatin works by interfering with the [[DNA]] in cancer cells, preventing them from dividing and growing. It forms covalent bonds with the DNA, causing the DNA strands to cross-link and inhibiting DNA synthesis and function. This leads to cell death and the reduction of the tumor.<br /> <br /> == Uses ==<br /> <br /> Nedaplatin is used in the treatment of various types of cancer. It is often used in combination with other chemotherapy drugs to increase its effectiveness. The types of cancer it is used to treat include:<br /> <br /> * [[Lung cancer]]<br /> * [[Esophageal cancer]]<br /> * [[Cervical cancer]]<br /> * [[Head and neck cancer]]<br /> <br /> == Side Effects ==<br /> <br /> Like all chemotherapy drugs, Nedaplatin can cause side effects. These can vary from person to person and depend on the dosage and length of treatment. Common side effects include:<br /> <br /> * [[Nausea]] and [[vomiting]]<br /> * [[Fatigue]]<br /> * [[Hair loss]]<br /> * [[Anemia]]<br /> * [[Neutropenia]] (low white blood cell count)<br /> <br /> == See Also ==<br /> <br /> * [[Chemotherapy]]<br /> * [[Cisplatin]]<br /> * [[Cancer treatment]]<br /> <br /> == References ==<br /> <br /> &lt;references /&gt;<br /> <br /> [[Category:Chemotherapy]]<br /> [[Category:Cancer treatment]]<br /> [[Category:Drugs]]<br /> {{Chemotherapy}}<br /> {{Cancer treatment}}<br /> {{Pharmacology-stub}}</div>

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