https://wikimd.org/index.php?action=history&feed=atom&title=MorantelMorantel - Revision history2026-04-25T14:32:51ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Morantel&diff=6346868&oldid=prevPrab: CSV import2025-02-25T12:02:23Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Morantel''' is an [[anthelmintic]] drug used primarily in the treatment of [[parasitic worm]] infections in animals. It belongs to the class of drugs known as [[tetrahydropyrimidines]], which also includes [[pyrantel]] and [[oxantel]]. Morantel is not typically used in humans, but it is an important tool in [[veterinary medicine]].<br />
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== Mechanism of Action ==<br />
Morantel works by acting on the [[neuromuscular junction]] of the parasitic worms. It causes a persistent activation of the [[nicotinic acetylcholine receptors]] on the worm's muscle cells, leading to paralysis and expulsion of the worm from the host organism.<br />
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== Uses ==<br />
Morantel is primarily used in the treatment of [[nematode]] infections in livestock, particularly [[sheep]] and [[goats]]. It is effective against a variety of nematodes, including those in the genera ''[[Haemonchus]]'', ''[[Trichostrongylus]]'', and ''[[Ostertagia]]''.<br />
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== Side Effects ==<br />
As with any medication, morantel can cause side effects. In animals, these can include [[salivation]], [[vomiting]], and [[diarrhea]]. However, these side effects are generally rare and mild.<br />
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== Resistance ==<br />
Resistance to morantel and other tetrahydropyrimidines has been reported in some nematode populations. This is a significant concern in veterinary medicine, as it can limit the effectiveness of these drugs.<br />
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== See Also ==<br />
* [[Pyrantel]]<br />
* [[Oxantel]]<br />
* [[Anthelmintic resistance]]<br />
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[[Category:Veterinary drugs]]<br />
[[Category:Anthelmintics]]<br />
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