https://wikimd.org/index.php?action=history&feed=atom&title=Moperone 2026-04-26T12:02:24Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Moperone&diff=6335267&oldid=prev 2025-02-20T01:36:51Z

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<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Moperone&#039;&#039;&#039; is a [[typical antipsychotic]] medication that belongs to the [[butyrophenone]] class of drugs. It is primarily used in the treatment of [[schizophrenia]] and other [[psychotic disorders]]. Moperone is not widely used due to its potential side effects and the availability of safer alternatives.<br /> <br /> ==Pharmacology==<br /> Moperone acts by blocking [[dopamine receptors]] in the brain, specifically the D2 subtype. This reduces the overactivity of dopamine, which is thought to be a contributing factor in the development of psychotic symptoms. Moperone also has some affinity for the D1 subtype, but this is less significant in terms of its antipsychotic effects.<br /> <br /> ==Clinical Use==<br /> Moperone is used in the treatment of schizophrenia and other psychotic disorders. It can help to reduce symptoms such as hallucinations, delusions, and disorganized thinking. However, it is not a first-line treatment and is typically only used when other antipsychotic medications have not been effective.<br /> <br /> ==Side Effects==<br /> The side effects of Moperone can include [[extrapyramidal symptoms]] such as tremors, rigidity, and bradykinesia. It can also cause [[tardive dyskinesia]], a condition characterized by involuntary movements of the face and body. Other potential side effects include sedation, weight gain, and [[anticholinergic effects]] such as dry mouth and blurred vision.<br /> <br /> ==History==<br /> Moperone was first synthesized in the 1960s as part of a series of butyrophenone derivatives. It was initially marketed as a potent antipsychotic with fewer side effects than older drugs in the same class. However, its use has declined over time due to the development of newer, safer antipsychotic medications.<br /> <br /> ==See Also==<br /> * [[Antipsychotic]]<br /> * [[Butyrophenone]]<br /> * [[Schizophrenia]]<br /> * [[Psychotic disorders]]<br /> <br /> [[Category:Antipsychotics]]<br /> [[Category:Butyrophenones]]<br /> [[Category:Medications]]<br /> <br /> {{Pharma-stub}}<br /> {{Medicine-stub}}</div>

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