https://wikimd.org/index.php?action=history&feed=atom&title=MometasoneMometasone - Revision history2026-04-26T19:58:03ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Mometasone&diff=4963267&oldid=prevPrab at 17:33, 1 June 20232023-06-01T17:33:21Z<p></p>
<p><b>New page</b></p><div>'''Mometasone''' is a medium to high potency corticosteroid drug used in the treatment of various inflammatory and immune-mediated conditions. Mometasone primarily exerts its effects by suppressing inflammatory and immune responses, making it effective in managing conditions such as asthma, allergic rhinitis, and various skin disorders.<br />
[[File:Momate.jpg|thumb|Momate]]<br />
== Pharmacological Properties ==<br />
Mometasone is a [[Glucocorticoid|glucocorticoid]], a class of steroid hormones that exert potent anti-inflammatory and immunosuppressive effects. It acts by binding to the glucocorticoid receptor within cells, leading to the regulation of gene expression and a consequent decrease in the production of inflammatory mediators.<br />
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== Therapeutic Uses ==<br />
*Mometasone is available in several forms, each tailored for specific conditions:<br />
*'''Inhalation''': As an [[inhalation]] aerosol, mometasone is used for the long-term management of [[asthma]]. It reduces the swelling and inflammation in the airways, improving breathing and reducing the frequency of asthma attacks.<br />
*'''Topical''': In its [[topical]] formulation, mometasone is effective in treating various skin conditions such as [[eczema]], [[psoriasis]], and [[rashes]] due to allergies. It helps to reduce symptoms such as swelling, itching, and redness.<br />
*'''Nasal spray''': Mometasone [[nasal spray]] is commonly prescribed for the treatment of [[allergic rhinitis]] to control symptoms such as sneezing, itching, and a runny or stuffed nose.<br />
[[File:Mometasone furoate and formoterol.svg|thumb|Mometasone furoate and formoterol]]<br />
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== Side Effects and Precautions ==<br />
*As with all corticosteroids, mometasone use can lead to side effects. Common side effects include headaches, sore throat, and nasal dryness or irritation when used as a nasal spray; cough and dry mouth when used for inhalation; and itching, dryness, or burning when applied topically.<br />
*More serious but less common side effects can include adrenal suppression, growth retardation in children, and the development of [[glaucoma]] or [[cataracts]] with long-term use.<br />
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== References ==<br />
<references><br />
* [[National Center for Biotechnology Information]]. PubChem Compound Summary for CID 441335, Mometasone. Retrieved May 25, 2023 from https://pubchem.ncbi.nlm.nih.gov/compound/Mometasone.<br />
* Lipworth, B. J. (1999). Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis. ''Archives of Internal Medicine'', 159(9), 941-955.<br />
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{{stub}}<br />
[[Category: Glucocorticoids]]<br />
[[Category: Medications]]<br />
[[Category: Anti-inflammatory drugs]]</div>Prab