Prab: CSV import

2024-12-29T17:02:27Z

CSV import

← Older revision		Revision as of 17:02, 29 December 2024
Line 1:		Line 1:
	~~== Migrating Motor Complex ==~~

	~~[[File:Gastrointestinal tract.svg~~\|~~thumb~~\|~~right~~\|~~300px~~\|~~Illustration of the human gastrointestinal tract]]~~		{{Infobox medical condition
			\| name = Migrating Motor Complex
			\| image = <!-- Image removed -->
			\| caption = <!-- Caption removed -->
			\| field = Gastroenterology
			}}

	The '''Migrating Motor Complex''' (MMC) is a pattern of ~~electrical~~ activity ~~that occurs~~ in ~~the~~ [[gastrointestinal ~~tract~~]] ~~in a regular cycle~~ during ~~fasting~~. It ~~was first described by Vantrappen et al. in 1977. The MMC~~ is ~~responsible for the rumbling experienced when hungry and is also thought to serve~~ a ~~"housekeeping" role and sweep residual undigested material through~~ the digestive ~~tube~~.		The '''Migrating Motor Complex''' (MMC) is a pattern of electromechanical activity observed in [[gastrointestinal physiology]] during the periods between meals. It is a crucial component of the [[digestive system]] that helps in maintaining gut motility and preventing bacterial overgrowth.

	== Phases ==		== Phases of the Migrating Motor Complex ==
			The MMC is divided into four distinct phases:

	~~The MMC operates~~ in ~~a cycle~~ that ~~is usually~~ about 90 to ~~120~~ minutes ~~long~~ and ~~is divided into four phases:~~		* '''Phase I''': A period of relative quiescence lasting 30 to 60 minutes, where there are no contractions.
			* '''Phase II''': A period of intermittent contractions that gradually increase in frequency and intensity.
			* '''Phase III''': Also known as the "housekeeper wave," this phase consists of intense, regular contractions that sweep along the length of the [[small intestine]]. It lasts about 5 to 10 minutes.
			* '''Phase IV''': A short transition period between phase III and phase I.

	~~# Phase I: A period of quiescence during which there are few contractions.~~		== Function ==
	~~# Phase II: A period~~ of ~~intermittent contractions due~~ to ~~irregular [[neural]] activity.~~		The primary function of the MMC is to clear residual undigested material from the stomach and small intestine. It also helps in:
	~~# Phase III: A period of regular contractions due to maximum neural activity~~. ~~This is~~ also ~~known as the "housekeeper wave".~~
	~~# Phase IV~~: ~~A short period of transition between phases III and I.~~

	[[~~File:MMC Phases~~.~~png\|thumb\|right\|300px\|Phases~~ of ~~the Migrating Motor Complex~~]]		* Preventing [[bacterial overgrowth]] in the small intestine.
			* Regulating the [[gastrointestinal tract]]'s motility.
			* Facilitating the transport of [[bile]] and [[pancreatic secretions]].

	== Regulation ==		== Regulation ==
			The MMC is regulated by both [[hormonal]] and [[neural]] mechanisms. The hormone [[motilin]] plays a significant role in initiating phase III of the MMC. Neural control involves the [[enteric nervous system]] and the [[autonomic nervous system]].
	The MMC is regulated by ~~several hormones~~ and ~~neurotransmitters, including~~ [[motilin]], [[~~serotonin~~]], and [[~~ghrelin~~]]~~. Motilin is the primary hormone responsible for the initiation of the MMC~~.

	== Clinical Significance ==		== Clinical Significance ==
			Disruption of the MMC can lead to various gastrointestinal disorders, such as:

	~~Disruption of the MMC can lead to a variety of gastrointestinal disorders, such as~~ [[~~gastroparesis]], [[small~~ intestinal bacterial overgrowth]] (SIBO)~~, and~~ [[~~irritable~~ bowel syndrome]] (IBS).		* [[Small intestinal bacterial overgrowth]] (SIBO)
			* [[Gastroparesis]]
			* [[Irritable bowel syndrome]] (IBS)

	== See Also ==		== See Also ==
			* [[Gastrointestinal motility]]
	* [[~~Gastrointestinal physiology~~]]		* [[Enteric nervous system]]
	* [[Motilin]]		* [[Motilin]]
	* [[Ghrelin]]

	== References ==		== References ==
			{{Reflist}}

	~~<references~~ />		== External Links ==
			* [https://www.wikimd.com/wiki/Migrating_motor_complex Migrating Motor Complex on WikiMD]

	[[Category:Gastroenterology]]		[[Category:Gastroenterology]]
	~~[[Category:Human physiology]]~~
	[[Category:Digestive system]]		[[Category:Digestive system]]
			[[Category:Physiology]]

Prab: CSV import

2024-02-01T16:30:48Z

CSV import

New page

== Migrating Motor Complex ==

[[File:Gastrointestinal tract.svg|thumb|right|300px|Illustration of the human gastrointestinal tract]]

The '''Migrating Motor Complex''' (MMC) is a pattern of electrical activity that occurs in the [[gastrointestinal tract]] in a regular cycle during fasting. It was first described by Vantrappen et al. in 1977. The MMC is responsible for the rumbling experienced when hungry and is also thought to serve a "housekeeping" role and sweep residual undigested material through the digestive tube.

== Phases ==

The MMC operates in a cycle that is usually about 90 to 120 minutes long and is divided into four phases:

# Phase I: A period of quiescence during which there are few contractions.
# Phase II: A period of intermittent contractions due to irregular [[neural]] activity.
# Phase III: A period of regular contractions due to maximum neural activity. This is also known as the "housekeeper wave".
# Phase IV: A short period of transition between phases III and I.

[[File:MMC Phases.png|thumb|right|300px|Phases of the Migrating Motor Complex]]

== Regulation ==

The MMC is regulated by several hormones and neurotransmitters, including [[motilin]], [[serotonin]], and [[ghrelin]]. Motilin is the primary hormone responsible for the initiation of the MMC.

== Clinical Significance ==

Disruption of the MMC can lead to a variety of gastrointestinal disorders, such as [[gastroparesis]], [[small intestinal bacterial overgrowth]] (SIBO), and [[irritable bowel syndrome]] (IBS).

== See Also ==

* [[Gastrointestinal physiology]]
* [[Motilin]]
* [[Ghrelin]]

== References ==

<references />

[[Category:Gastroenterology]]
[[Category:Human physiology]]
[[Category:Digestive system]]

Migrating motor complex - Revision history

Prab: CSV import

Prab: CSV import