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Metizolam - Revision history
2026-04-27T05:20:53Z
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2025-02-20T00:59:46Z
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Prab: CSV import
2024-03-08T18:31:35Z
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<p><b>New page</b></p><div>'''Metizolam''' (marketed under the brand name '''Tranzilam''') is a [[thienodiazepine]] drug which is a benzodiazepine analog. The effects of metizolam include [[anxiolytic]], [[drowsiness]], [[muscle relaxation]], and [[amnesia]] which are typical of such drugs. <br />
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==Pharmacology==<br />
Metizolam has been found to be roughly the same potency as [[diazepam]], but with a slightly longer half-life. It is metabolized in the liver into the active metabolite [[alpha-hydroxymetizolam]]. <br />
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==Medical Uses==<br />
Metizolam is used for the short-term treatment of [[insomnia]], [[anxiety]], and [[panic disorder]]. It is also used as a premedication for minor surgical procedures.<br />
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==Side Effects==<br />
Common side effects of metizolam include drowsiness, [[dizziness]], [[nausea]], and [[dry mouth]]. More serious side effects may include [[respiratory depression]], [[dependence]], and [[withdrawal syndrome]].<br />
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==Interactions==<br />
Metizolam may interact with other medications, including other [[CNS depressants]], [[alcohol]], and [[grapefruit juice]]. These interactions can increase the risk of side effects and should be avoided.<br />
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==Legal Status==<br />
In many countries, metizolam is a controlled substance due to its potential for abuse and dependence.<br />
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==See Also==<br />
* [[Benzodiazepine]]<br />
* [[Thienodiazepine]]<br />
* [[Diazepam]]<br />
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==References==<br />
<references /><br />
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[[Category:Thienodiazepines]]<br />
[[Category:Anxiolytics]]<br />
[[Category:Hypnotics]]<br />
[[Category:Sedatives]]<br />
[[Category:GABAA receptor positive allosteric modulators]]<br />
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{{pharmacology-stub}}</div>
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