https://wikimd.org/index.php?action=history&feed=atom&title=MethiopropamineMethiopropamine - Revision history2026-04-26T22:02:33ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Methiopropamine&diff=6415237&oldid=prevPrab: CSV import2025-03-03T04:58:31Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Methiopropamine''' (also known as '''MPA''') is a [[thiophene]]-ring-based structural analog of [[methamphetamine]] originally reported in 1942. Chemically it is not a [[phenethylamine]] or [[amphetamine]] and is not their functional analog either, which makes it a perfectly legal drug that circumvents even the anti-drug-analog laws. It has been sold as a [[designer drug]], first being identified in Sweden in the year 2010.<br />
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==Chemistry==<br />
Methiopropamine is related to methamphetamine in much the same way as [[thiopental]] is related to [[pentobarbital]]. It is not a [[barbiturate]] but it is a thiophene analog.<br />
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==Pharmacology==<br />
Methiopropamine functions as a selective [[norepinephrine]]-[[dopamine]] reuptake inhibitor with little to no effect on [[serotonin]] reuptake. Methiopropamine has a significantly reduced [[potency]] compared to methamphetamine, likely due to the added bulk of the thiophene ring. Methiopropamine is likely to be metabolized in a similar way to methamphetamine.<br />
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==Effects==<br />
The effects of methiopropamine are generally regarded as less intense than methamphetamine but longer lasting than the effects of [[cocaine]]. The effects have been described as euphoric, mentally stimulating, and physically stimulating. <br />
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==Legal Status==<br />
Methiopropamine is a controlled substance in some countries such as the UK, but remains legal in many other jurisdictions. It is often used as a research chemical and can be purchased online.<br />
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==See Also==<br />
* [[Amphetamine]]<br />
* [[Methamphetamine]]<br />
* [[Thiophene]]<br />
* [[Designer drug]]<br />
* [[Research chemical]]<br />
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[[Category:Psychoactive drugs]]<br />
[[Category:Stimulants]]<br />
[[Category:Thiophenes]]<br />
{{Psychoactive substance-stub}}<br />
{{Pharma-stub}}</div>Prab