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2025-04-13T10:11:50Z

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← Older revision		Revision as of 10:11, 13 April 2025
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			{{SI}}
			{{Infobox medical condition
			\| name = Merkel-cell carcinoma
			\| image = [[File:Merkel_cell_carcinoma_-_very_high_mag.jpg\|alt=Micrograph of Merkel-cell carcinoma]]
			\| caption = Micrograph of Merkel-cell carcinoma
			\| field = [[Oncology]]
			\| synonyms = [[Neuroendocrine carcinoma of the skin]], [[Trabecular carcinoma of the skin]]
			\| symptoms = [[Painless]], [[firm]], [[shiny]] skin nodule
			\| complications = [[Metastasis]]
			\| onset = Typically after age 50
			\| duration = Chronic
			\| causes = [[Merkel cell polyomavirus]], [[Ultraviolet light]] exposure
			\| risks = [[Immunosuppression]], [[fair skin]], [[excessive sun exposure]]
			\| diagnosis = [[Biopsy]] and [[histopathology]]
			\| differential = [[Basal cell carcinoma]], [[Squamous cell carcinoma]], [[Melanoma]]
			\| prevention = [[Sun protection]], [[avoidance of immunosuppression]]
			\| treatment = [[Surgery]], [[radiation therapy]], [[chemotherapy]], [[immunotherapy]]
			\| prognosis = Variable, depends on stage
			\| frequency = Rare
			}}
			[[File:Merkel_cell_carcinoma_arm.jpg\|Merkel cell carcinoma on arm\|thumb\|left]]
			[[File:Merkel_Cell_Carcinoma_buttock_45-year-old_woman.jpg\|Merkel cell carcinoma on buttock of 45-year-old woman\|thumb]]
			[[File:Merkelcellcarcinoma_Tag.jpg\|Merkel cell carcinoma tag\|thumb\|left]]
			[[File:Micrographs_of_a_typical_merkel_cell_carcinoma.jpg\|Micrographs of a typical Merkel cell carcinoma\|thumb]]
	'''Merkel-cell carcinoma''' ('''MCC''') is a rare and aggressive type of skin cancer that usually appears as a flesh-colored or bluish-red nodule, often on your face, head or neck. Merkel-cell carcinoma is also called '''neuroendocrine carcinoma of the skin'''.		'''Merkel-cell carcinoma''' ('''MCC''') is a rare and aggressive type of skin cancer that usually appears as a flesh-colored or bluish-red nodule, often on your face, head or neck. Merkel-cell carcinoma is also called '''neuroendocrine carcinoma of the skin'''.

	== Causes ==		== Causes ==
	MCC is believed to be caused by a combination of factors, including long-term sun exposure and a weakened immune system. The Merkel cell polyomavirus (MCPyV) is also associated with most cases of MCC.		MCC is believed to be caused by a combination of factors, including long-term sun exposure and a weakened immune system. The Merkel cell polyomavirus (MCPyV) is also associated with most cases of MCC.

	== Symptoms ==		== Symptoms ==
	The most common symptom of MCC is a fast-growing, painless nodule (bump) on your skin. The nodule may be skin-colored or may appear in shades of red, blue or purple. Most often, the nodule will appear on a sun-exposed area, such as your face, neck or scalp.		The most common symptom of MCC is a fast-growing, painless nodule (bump) on your skin. The nodule may be skin-colored or may appear in shades of red, blue or purple. Most often, the nodule will appear on a sun-exposed area, such as your face, neck or scalp.

	== Diagnosis ==		== Diagnosis ==
	Diagnosis of MCC often involves a skin biopsy, where a sample of the suspicious skin is removed and examined under a microscope. Other tests, such as imaging tests and sentinel lymph node biopsy, may also be used to determine the extent of the cancer.		Diagnosis of MCC often involves a skin biopsy, where a sample of the suspicious skin is removed and examined under a microscope. Other tests, such as imaging tests and sentinel lymph node biopsy, may also be used to determine the extent of the cancer.

	== Treatment ==		== Treatment ==
	Treatment options for MCC include surgery, radiation therapy, and chemotherapy. In some cases, a combination of these treatments may be used. Immunotherapy is a newer treatment option that uses the body's immune system to fight the cancer.		Treatment options for MCC include surgery, radiation therapy, and chemotherapy. In some cases, a combination of these treatments may be used. Immunotherapy is a newer treatment option that uses the body's immune system to fight the cancer.

	== Prognosis ==		== Prognosis ==
	The prognosis for MCC varies greatly depending on the stage of the disease at diagnosis. Early detection and treatment can significantly improve the prognosis.		The prognosis for MCC varies greatly depending on the stage of the disease at diagnosis. Early detection and treatment can significantly improve the prognosis.

	== See also ==		== See also ==
	* [[Skin cancer]]		* [[Skin cancer]]
	* [[Merkel cell]]		* [[Merkel cell]]
	* [[Immunotherapy]]		* [[Immunotherapy]]

	== References ==		== References ==
	<references />		<references />

	[[Category:Skin cancers]]		[[Category:Skin cancers]]
	[[Category:Rare diseases]]		[[Category:Rare diseases]]
	[[Category:Oncology]]		[[Category:Oncology]]
	{{stub}}		{{stub}}
	~~<gallery>~~
	~~File:Merkel_cell_carcinoma_-_very_high_mag.jpg\|Merkel cell carcinoma - very high magnification~~
	~~File:Merkel_cell_carcinoma_arm.jpg\|Merkel cell carcinoma on arm~~
	~~File:Merkel_Cell_Carcinoma_buttock_45-year-old_woman.jpg\|Merkel cell carcinoma on buttock of 45-year-old woman~~
	~~File:Merkelcellcarcinoma_Tag.jpg\|Merkel cell carcinoma tag~~
	~~File:Micrographs_of_a_typical_merkel_cell_carcinoma.jpg\|Micrographs of a typical Merkel cell carcinoma~~
	~~</gallery>~~

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2025-02-18T04:38:10Z

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← Older revision		Revision as of 04:38, 18 February 2025
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	[[Category:Oncology]]		[[Category:Oncology]]
	{{stub}}		{{stub}}
			<gallery>
			File:Merkel_cell_carcinoma_-_very_high_mag.jpg\|Merkel cell carcinoma - very high magnification
			File:Merkel_cell_carcinoma_arm.jpg\|Merkel cell carcinoma on arm
			File:Merkel_Cell_Carcinoma_buttock_45-year-old_woman.jpg\|Merkel cell carcinoma on buttock of 45-year-old woman
			File:Merkelcellcarcinoma_Tag.jpg\|Merkel cell carcinoma tag
			File:Micrographs_of_a_typical_merkel_cell_carcinoma.jpg\|Micrographs of a typical Merkel cell carcinoma
			</gallery>

Prab: CSV import

2024-02-22T03:48:12Z

CSV import

New page

'''Merkel-cell carcinoma''' ('''MCC''') is a rare and aggressive type of skin cancer that usually appears as a flesh-colored or bluish-red nodule, often on your face, head or neck. Merkel-cell carcinoma is also called '''neuroendocrine carcinoma of the skin'''.

== Causes ==
MCC is believed to be caused by a combination of factors, including long-term sun exposure and a weakened immune system. The Merkel cell polyomavirus (MCPyV) is also associated with most cases of MCC.

== Symptoms ==
The most common symptom of MCC is a fast-growing, painless nodule (bump) on your skin. The nodule may be skin-colored or may appear in shades of red, blue or purple. Most often, the nodule will appear on a sun-exposed area, such as your face, neck or scalp.

== Diagnosis ==
Diagnosis of MCC often involves a skin biopsy, where a sample of the suspicious skin is removed and examined under a microscope. Other tests, such as imaging tests and sentinel lymph node biopsy, may also be used to determine the extent of the cancer.

== Treatment ==
Treatment options for MCC include surgery, radiation therapy, and chemotherapy. In some cases, a combination of these treatments may be used. Immunotherapy is a newer treatment option that uses the body's immune system to fight the cancer.

== Prognosis ==
The prognosis for MCC varies greatly depending on the stage of the disease at diagnosis. Early detection and treatment can significantly improve the prognosis.

== See also ==
* [[Skin cancer]]
* [[Merkel cell]]
* [[Immunotherapy]]

== References ==
<references />

[[Category:Skin cancers]]
[[Category:Rare diseases]]
[[Category:Oncology]]
{{stub}}

Merkel-cell carcinoma - Revision history

Prab: CSV import

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