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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=MVA85A</id>
	<title>MVA85A - Revision history</title>
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	<updated>2026-04-26T03:52:31Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=MVA85A&amp;diff=6513086&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=MVA85A&amp;diff=6513086&amp;oldid=prev"/>
		<updated>2025-03-17T18:30:04Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 18:30, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=MVA85A&amp;diff=6258253&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=MVA85A&amp;diff=6258253&amp;oldid=prev"/>
		<updated>2025-02-10T20:52:00Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 20:52, 10 February 2025&lt;/td&gt;
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		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=MVA85A&amp;diff=5297467&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=MVA85A&amp;diff=5297467&amp;oldid=prev"/>
		<updated>2024-02-25T20:56:06Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;MVA85A&amp;#039;&amp;#039;&amp;#039; is a [[tuberculosis]] [[vaccine]] candidate that is currently under investigation. It is designed to be a booster to the [[BCG vaccine]], the only currently available vaccine against tuberculosis. MVA85A is the first new tuberculosis vaccine candidate to reach [[Phase IIb clinical trials]] since the BCG vaccine was introduced in 1921.&lt;br /&gt;
&lt;br /&gt;
== History ==&lt;br /&gt;
MVA85A was developed by researchers at the [[University of Oxford]]. The vaccine candidate entered Phase IIb clinical trials in 2009, making it the first new tuberculosis vaccine candidate to reach this stage of development in nearly a century.&lt;br /&gt;
&lt;br /&gt;
== Design ==&lt;br /&gt;
MVA85A is designed to boost the immune response initiated by the BCG vaccine. It is a modified [[vaccinia]] virus that expresses the [[antigen]] 85A from &amp;#039;&amp;#039;[[Mycobacterium tuberculosis]]&amp;#039;&amp;#039;. &lt;br /&gt;
&lt;br /&gt;
== Clinical trials ==&lt;br /&gt;
In 2013, results from a Phase IIb clinical trial in South Africa were published. The trial involved nearly 3,000 infants who had previously been vaccinated with BCG. The results showed that MVA85A did not significantly boost the efficacy of the BCG vaccine.&lt;br /&gt;
&lt;br /&gt;
== Future development ==&lt;br /&gt;
Despite the disappointing results of the Phase IIb trial, research into MVA85A continues. Future trials may focus on different populations, such as adults or individuals with [[HIV]].&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Tuberculosis vaccine]]&lt;br /&gt;
* [[BCG vaccine]]&lt;br /&gt;
* [[Vaccinia]]&lt;br /&gt;
* [[Mycobacterium tuberculosis]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Vaccines]]&lt;br /&gt;
[[Category:Tuberculosis]]&lt;br /&gt;
[[Category:Clinical trials]]&lt;br /&gt;
&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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