https://wikimd.com/index.php?action=history&feed=atom&title=MT-TL2 MT-TL2 - Revision history 2026-04-22T05:26:52Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=MT-TL2&diff=6513115&oldid=prev Prab: CSV import 2025-03-17T18:32:23Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:32, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l26">Line 26:</td> <td colspan="2" class="diff-lineno">Line 26:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Transfer RNA]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Transfer RNA]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=MT-TL2&diff=6272349&oldid=prev Prab: CSV import 2025-02-11T03:31:37Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 03:31, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l25">Line 25:</td> <td colspan="2" class="diff-lineno">Line 25:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Mitochondrial genes]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Mitochondrial genes]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Transfer RNA]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Transfer RNA]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=MT-TL2&diff=5380330&oldid=prev Prab: CSV import 2024-03-10T07:29:15Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;MT-TL2&#039;&#039;&#039; is a [[gene]] that in humans is located on [[mitochondrial DNA]]. It encodes the [[transfer RNA]] for [[leucine]] (tRNA^Leu(UUR)), which is essential for the synthesis of [[protein]]s within the [[mitochondrion]]. Mutations in this gene have been associated with various [[mitochondrial disease|mitochondrial diseases]], including [[mitochondrial encephalomyopathy]], [[lactic acidosis]], and [[stroke-like syndrome]] (MELAS).<br /> <br /> ==Structure==<br /> The MT-TL2 gene is located in the [[mitochondrial genome]], specifically at base pairs 12207 to 12265. It is a small gene, consisting of only 59 base pairs. The gene is part of the heavy strand of mitochondrial DNA, which contains most of the genes involved in mitochondrial protein synthesis.<br /> <br /> ==Function==<br /> The MT-TL2 gene encodes the tRNA^Leu(UUR), which is responsible for the incorporation of the amino acid leucine into growing polypeptide chains during protein synthesis. This process takes place within the mitochondrion, the cell&#039;s powerhouse, where energy is produced.<br /> <br /> ==Clinical significance==<br /> Mutations in the MT-TL2 gene have been linked to several mitochondrial diseases. These include MELAS, a condition characterized by recurrent [[stroke]]-like episodes, [[muscle weakness]], and a buildup of lactic acid in the body. Other conditions associated with MT-TL2 mutations include [[myoclonic epilepsy with ragged-red fibers]] (MERRF), [[Leber&#039;s hereditary optic neuropathy]] (LHON), and [[neuropathy]], [[ataxia]], and [[retinitis pigmentosa]] (NARP).<br /> <br /> ==See also==<br /> * [[Mitochondrial DNA]]<br /> * [[Mitochondrial disease]]<br /> * [[Transfer RNA]]<br /> <br /> ==References==<br /> &lt;references/&gt;<br /> <br /> {{Genes on human chromosome MT}}<br /> {{Mitochondrial diseases}}<br /> {{medicine-stub}}<br /> <br /> [[Category:Genes on human chromosome MT]]<br /> [[Category:Mitochondrial genes]]<br /> [[Category:Transfer RNA]]</div> Prab