https://wikimd.org/index.php?action=history&feed=atom&title=MT-TL1 MT-TL1 - Revision history 2026-04-26T03:32:59Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=MT-TL1&diff=6513111&oldid=prev Prab: CSV import 2025-03-17T18:32:10Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:32, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=MT-TL1&diff=6267537&oldid=prev Prab: CSV import 2025-02-11T01:08:15Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:08, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Genetics-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Genetics-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=MT-TL1&diff=5378817&oldid=prev Prab: CSV import 2024-03-10T05:39:40Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;MT-TL1&#039;&#039;&#039; is a [[gene]] that in humans is responsible for encoding the [[mitochondrial]] [[tRNA]] for [[leucine]]. This gene is located within the [[mitochondrial DNA]], specifically in the [[mitochondrial genome]]. Mutations in this gene have been associated with various diseases, including [[mitochondrial encephalomyopathy]], [[lactic acidosis]], and [[stroke-like episodes]] (MELAS), [[myoclonic epilepsy with ragged-red fibers]] (MERRF), and [[Leber&#039;s hereditary optic neuropathy]] (LHON).<br /> <br /> ==Structure==<br /> The MT-TL1 gene is located on the [[mitochondrial genome]] at position 3230-3304. It is a small gene, consisting of only 75 [[base pairs]]. The structure of the MT-TL1 gene is unique in that it lacks [[introns]], a characteristic feature of mitochondrial genes. <br /> <br /> ==Function==<br /> The MT-TL1 gene encodes the mitochondrial [[tRNA]] for [[leucine]]. tRNA is a type of [[RNA]] molecule that helps decode a [[messenger RNA]] (mRNA) sequence into a protein. In this case, the MT-TL1 gene helps in the synthesis of proteins that are essential for the normal functioning of the [[mitochondria]].<br /> <br /> ==Clinical significance==<br /> Mutations in the MT-TL1 gene have been associated with several mitochondrial diseases. These include:<br /> <br /> * &#039;&#039;&#039;[[Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes]] (MELAS)&#039;&#039;&#039;: This is a condition that affects many of the body&#039;s systems, particularly the brain and nervous system (encephalo-) and muscles (myopathy). <br /> <br /> * &#039;&#039;&#039;[[Myoclonic epilepsy with ragged-red fibers]] (MERRF)&#039;&#039;&#039;: This is a disorder that affects many parts of the body, particularly the muscles and nervous system. <br /> <br /> * &#039;&#039;&#039;[[Leber&#039;s hereditary optic neuropathy]] (LHON)&#039;&#039;&#039;: This is an inherited form of vision loss that predominantly affects males.<br /> <br /> ==See also==<br /> * [[Mitochondrial DNA]]<br /> * [[Mitochondrial disease]]<br /> * [[tRNA]]<br /> * [[Leucine]]<br /> <br /> [[Category:Genes]]<br /> [[Category:Mitochondrial diseases]]<br /> [[Category:Genetic diseases]]<br /> <br /> {{Genetics-stub}}<br /> {{medicine-stub}}</div> Prab