https://wikimd.org/index.php?action=history&feed=atom&title=MMP10 2026-05-12T15:07:54Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=MMP10&diff=6512861&oldid=prev 2025-03-17T18:13:01Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:13, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Metabolic pathways]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Metabolic pathways]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=MMP10&diff=6272521&oldid=prev 2025-02-11T03:35:33Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 03:35, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Genetic disorders]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Genetic disorders]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Metabolic pathways]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Metabolic pathways]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=MMP10&diff=6022663&oldid=prev 2024-12-02T02:20:32Z

<p>CSV import</p> <p><b>New page</b></p><div>MLYCD<br /> <br /> The MLYCD gene encodes the enzyme malonyl-CoA decarboxylase, which is crucial in fatty acid metabolism. This enzyme catalyzes the decarboxylation of malonyl-CoA to acetyl-CoA and carbon dioxide, a reaction that plays a significant role in regulating the levels of malonyl-CoA, a key molecule in the synthesis and oxidation of fatty acids.<br /> <br /> == Function ==<br /> Malonyl-CoA decarboxylase is an enzyme that helps maintain the balance between fatty acid synthesis and oxidation. Malonyl-CoA is an inhibitor of carnitine palmitoyltransferase 1 (CPT1), the enzyme responsible for transporting fatty acids into the mitochondria for β-oxidation. By converting malonyl-CoA to acetyl-CoA, MLYCD reduces the inhibition of CPT1, thereby promoting fatty acid oxidation.<br /> <br /> == Clinical Significance ==<br /> Mutations in the MLYCD gene can lead to malonyl-CoA decarboxylase deficiency, a rare metabolic disorder characterized by the accumulation of malonyl-CoA. This condition can result in developmental delay, cardiomyopathy, metabolic acidosis, and other symptoms. Early diagnosis and management are crucial for improving outcomes in affected individuals.<br /> <br /> == Genetic Information ==<br /> The MLYCD gene is located on chromosome 16q23.3. It consists of multiple exons and encodes a protein that is expressed in various tissues, including the liver, heart, and brain. The gene is subject to alternative splicing, resulting in different isoforms of the enzyme.<br /> <br /> == Research and Developments ==<br /> Ongoing research is focused on understanding the regulation of MLYCD expression and activity, as well as its role in metabolic diseases. Studies are also exploring potential therapeutic approaches for malonyl-CoA decarboxylase deficiency, including gene therapy and enzyme replacement therapy.<br /> <br /> == Also see ==<br /> * [[Fatty acid metabolism]]<br /> * [[Carnitine palmitoyltransferase I]]<br /> * [[Metabolic disorders]]<br /> * [[Enzyme replacement therapy]]<br /> <br /> {{Enzyme-stub}}<br /> {{Genetics-stub}}<br /> <br /> [[Category:Enzymes]]<br /> [[Category:Genetic disorders]]<br /> [[Category:Metabolic pathways]]</div>

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