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	~~'''~~MDMAT''' (or '''3,4-Methylenedioxy-N-methylamphetamine''') is a [[psychoactive drug]] of the [[substituted amphetamine]] chemical class, known for its effects as a [[empathogen-entactogen]], [[stimulant]], and [[psychedelic]]. It is more commonly known by its street names, '''Ecstasy''' or '''Molly'''.		{{DISPLAYTITLE:MDMAT}}

	== ~~History~~ ==		== Overview ==
			'''MDMAT''' (3,4-methylenedioxy-N-methylamphetamine) is a synthetic [[psychoactive drug]] belonging to the [[amphetamine]] class. It is structurally related to [[MDMA]] (3,4-methylenedioxy-N-methylamphetamine), commonly known as ecstasy. MDMAT is known for its stimulant and [[empathogenic]] effects, which are similar to those of MDMA.

	~~MDMAT was first synthesized in 1912 by the pharmaceutical company~~ [[~~Merck (company)~~\|~~Merck~~]]~~. It was initially patented for use as an appetite suppressant~~, ~~but this application was never marketed~~. The ~~drug gained significant popularity in~~ the ~~1980s and 1990s as~~ a ~~component~~ in ~~the [[rave]] and [[clubbing]] scenes~~.		== Chemical Structure ==
			[[File:MDMAT-structure.png\|thumb\|right\|Chemical structure of MDMAT]]
			MDMAT is characterized by the presence of a methylenedioxy group attached to the phenyl ring, similar to MDMA. The chemical structure of MDMAT includes a methyl group attached to the nitrogen atom, which is a common feature in many amphetamines.

	== Pharmacology ==		== Pharmacology ==
			MDMAT acts primarily as a [[serotonin]] releasing agent, similar to MDMA. It increases the levels of serotonin, [[dopamine]], and [[norepinephrine]] in the brain, leading to its psychoactive effects. The increase in serotonin levels is responsible for the empathogenic effects, while the increase in dopamine and norepinephrine contributes to its stimulant properties.
	MDMAT ~~works~~ primarily ~~by increasing the activity of three neurotransmitters in the brain:~~ [[serotonin]], [[dopamine]], and [[norepinephrine]]~~. It achieves this by inhibiting their reuptake and promoting their release~~, leading to ~~an overall~~ increase in the ~~concentrations of these neurotransmitters~~.

	== Effects ==		== Effects ==
			The effects of MDMAT are similar to those of MDMA, including increased energy, enhanced sensory perception, and feelings of emotional closeness and empathy. Users may also experience [[euphoria]], increased sociability, and a sense of well-being. However, like other amphetamines, MDMAT can also cause adverse effects such as [[anxiety]], [[insomnia]], and [[tachycardia]].
	The effects of MDMAT ~~can vary widely depending on the dose~~, ~~the user's individual physiology~~, and ~~the environment in which it's taken. Common effects include~~ feelings of euphoria, increased sociability~~, heightened sensory perception~~, and ~~increased energy~~. However, it can also cause ~~a range of negative side~~ effects, ~~including dehydration, hyperthermia, bruxism~~, and ~~in rare cases, severe neurological damage~~.

	== Legal Status ==		== Legal Status ==
			The legal status of MDMAT varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is important to consult local laws to determine the legal status of MDMAT in a specific region.

	MDMAT is ~~classified~~ as a [[~~Schedule I drug~~]] ~~under the~~ [[~~United Nations Convention on Psychotropic Substances~~]], ~~meaning it is considered to have a high potential for abuse~~ and ~~no accepted medical use. However, some research suggests that it may have potential therapeutic uses in the treatment of~~ [[~~post-traumatic stress disorder~~]] and ~~other mental health conditions~~.		== Related Compounds ==
			MDMAT is part of a larger family of [[substituted amphetamines]], which includes other compounds such as [[MDMA]], [[MDA]], and [[MDEA]]. These compounds share similar chemical structures and pharmacological effects, but differ in their potency and duration of action.

	== ~~See Also~~ ==		== Related Pages ==
			* [[MDMA]]
	* [[Amphetamine]]		* [[Amphetamine]]
	* [[~~Psychedelic~~ drug]]		* [[Psychoactive drug]]
	* [[~~Recreational drug use~~]]		* [[Serotonin]]

	~~== References ==~~
	~~<references />~~

	[[Category:Psychoactive drugs]]		[[Category:Psychoactive drugs]]
	[[Category:Amphetamines]]		[[Category:Amphetamines]]
	~~[[Category:Entactogens]]~~
	~~{{Psychoactive drug-stub}}~~
	~~{{medicine-stub}}~~

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2024-02-29T03:06:26Z

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'''MDMAT''' (or '''3,4-Methylenedioxy-N-methylamphetamine''') is a [[psychoactive drug]] of the [[substituted amphetamine]] chemical class, known for its effects as a [[empathogen-entactogen]], [[stimulant]], and [[psychedelic]]. It is more commonly known by its street names, '''Ecstasy''' or '''Molly'''.

== History ==

MDMAT was first synthesized in 1912 by the pharmaceutical company [[Merck (company)|Merck]]. It was initially patented for use as an appetite suppressant, but this application was never marketed. The drug gained significant popularity in the 1980s and 1990s as a component in the [[rave]] and [[clubbing]] scenes.

== Pharmacology ==

MDMAT works primarily by increasing the activity of three neurotransmitters in the brain: [[serotonin]], [[dopamine]], and [[norepinephrine]]. It achieves this by inhibiting their reuptake and promoting their release, leading to an overall increase in the concentrations of these neurotransmitters.

== Effects ==

The effects of MDMAT can vary widely depending on the dose, the user's individual physiology, and the environment in which it's taken. Common effects include feelings of euphoria, increased sociability, heightened sensory perception, and increased energy. However, it can also cause a range of negative side effects, including dehydration, hyperthermia, bruxism, and in rare cases, severe neurological damage.

== Legal Status ==

MDMAT is classified as a [[Schedule I drug]] under the [[United Nations Convention on Psychotropic Substances]], meaning it is considered to have a high potential for abuse and no accepted medical use. However, some research suggests that it may have potential therapeutic uses in the treatment of [[post-traumatic stress disorder]] and other mental health conditions.

== See Also ==
* [[Amphetamine]]
* [[Psychedelic drug]]
* [[Recreational drug use]]

== References ==
<references />

[[Category:Psychoactive drugs]]
[[Category:Amphetamines]]
[[Category:Entactogens]]
{{Psychoactive drug-stub}}
{{medicine-stub}}

MDMAT - Revision history

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