Prab at 12:59, 18 March 2025

2025-03-18T12:59:51Z

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'''MAP''' or '''Mitogen-Activated Protein''' kinases are a type of protein kinase that are specific to the amino acids serine and threonine. They are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis.

== Function ==

[[MAP kinases]] are involved in directing cellular responses to a diverse array of stimuli, such as [[mitogens]], [[osmotic stress]], [[heat shock]] and [[proinflammatory cytokines]]. They regulate cell functions including [[proliferation]], [[gene expression]], [[differentiation]], [[mitosis]], [[cell survival]], and [[apoptosis]].

== Types ==

There are several types of MAP kinases, including [[ERK]], [[JNK]], and [[p38]]. Each of these is involved in a specific cellular response.

=== ERK ===

[[ERK]] or Extracellular signal–regulated kinases are a type of MAP kinase that is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.

=== JNK ===

[[JNK]] or c-Jun N-terminal kinases are a type of MAP kinase that is involved in the regulation of apoptosis and inflammatory responses.

=== p38 ===

[[p38]] MAP kinases are a type of MAP kinase that is involved in the regulation of cellular responses to cytokines and stress.

== See also ==

* [[Protein kinase]]
* [[Mitogen]]
* [[Cell proliferation]]
* [[Gene expression]]
* [[Cell differentiation]]
* [[Mitosis]]
* [[Apoptosis]]

[[Category:Protein kinases]]
[[Category:Cell biology]]
[[Category:Molecular biology]]
[[Category:Biochemistry]]

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MAP - Revision history

Prab at 12:59, 18 March 2025

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