https://wikimd.com/index.php?action=history&feed=atom&title=MAFG 2026-04-21T03:31:39Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=MAFG&diff=6513184&oldid=prev 2025-03-17T18:37:40Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:37, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.com/index.php?title=MAFG&diff=6272351&oldid=prev 2025-02-11T03:31:42Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 03:31, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.com/index.php?title=MAFG&diff=5379661&oldid=prev 2024-03-10T06:39:52Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;MAFG&#039;&#039;&#039; is a gene that encodes a protein in humans. This protein is part of the [[BRCA1]]-associated genome surveillance complex (BASC), which is involved in the recognition and repair of aberrant [[DNA]] structures. The BASC complex is thought to serve as a molecular sensor that binds to DNA structures associated with [[DNA damage]] or improper DNA repair, such as [[DNA double-strand breaks]] and [[interstrand cross-links]]. The MAFG protein is also a component of the [[Nrf2]]-[[Keap1]] complex, a critical regulator of cellular response to oxidative stress.<br /> <br /> == Function ==<br /> <br /> The MAFG gene encodes a small [[transcription factor]] that is a member of the MAF family. The encoded protein plays a role in many cellular processes, including cell differentiation and cell cycle regulation. In addition, it is involved in the regulation of [[antioxidant]] response elements (AREs) in target genes, and it plays a crucial role in cellular defense against toxic insults from both endogenous and exogenous sources.<br /> <br /> == Clinical Significance ==<br /> <br /> Alterations in the MAFG gene have been associated with several diseases. For example, mutations in this gene have been linked to [[cancer]], particularly [[breast cancer]] and [[lung cancer]]. This is likely due to the gene&#039;s role in DNA repair and response to oxidative stress, which are critical processes in the prevention of cancer development.<br /> <br /> == Research ==<br /> <br /> Research into the MAFG gene and its associated protein is ongoing. Current areas of focus include understanding the precise role of this gene in DNA repair and oxidative stress response, as well as investigating potential therapeutic applications. For example, drugs that can modulate the activity of the MAFG protein may be useful in the treatment of diseases associated with oxidative stress, such as cancer and [[neurodegenerative diseases]].<br /> <br /> == See Also ==<br /> * [[BRCA1]]<br /> * [[DNA repair]]<br /> * [[Oxidative stress]]<br /> * [[Transcription factor]]<br /> * [[Antioxidant response elements]]<br /> <br /> [[Category:Genes]]<br /> [[Category:DNA repair]]<br /> [[Category:Oxidative stress]]<br /> [[Category:Transcription factors]]<br /> [[Category:Antioxidant response elements]]<br /> <br /> {{medicine-stub}}</div>

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