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<p><b>New page</b></p><div>[[File:Lixivaptan.png|thumb|{{PAGENAME}}]]<br>'''Lixivaptan''' is a [[vasopressin receptor antagonist]] used in the treatment of [[hyponatremia]] (low blood sodium levels) associated with conditions like [[congestive heart failure]], [[cirrhosis]], and the [[syndrome of inappropriate antidiuretic hormone]] (SIADH). It is developed by [[Cardiokine Inc.]], a biopharmaceutical company focused on the discovery and development of new treatments for cardiovascular diseases.<br />
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== Mechanism of Action ==<br />
Lixivaptan works by blocking the action of [[vasopressin]], a hormone that regulates the body's water balance. It specifically targets the [[vasopressin V2 receptor]], which is primarily found in the [[kidney]]s. By blocking this receptor, Lixivaptan increases the excretion of water in the urine, thereby increasing the concentration of sodium in the blood.<br />
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== Clinical Trials ==<br />
Lixivaptan has undergone several [[clinical trial]]s to evaluate its safety and efficacy. In a Phase III clinical trial, Lixivaptan was shown to be effective in correcting hyponatremia in patients with heart failure and SIADH. However, the drug has not yet received approval from the [[Food and Drug Administration]] (FDA).<br />
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== Side Effects ==<br />
Common side effects of Lixivaptan include dry mouth, thirst, and increased urination. In some cases, it may also cause a rapid increase in blood sodium levels, which can lead to serious complications such as [[osmotic demyelination syndrome]].<br />
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== See Also ==<br />
* [[Vasopressin receptor antagonist]]<br />
* [[Hyponatremia]]<br />
* [[Congestive heart failure]]<br />
* [[Cirrhosis]]<br />
* [[Syndrome of inappropriate antidiuretic hormone]]<br />
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{{Medication-stub}}<br />
[[Category:Drugs]]<br />
[[Category:Vasopressin receptor antagonists]]<br />
[[Category:Hyponatremia]]<br />
[[Category:Cardiokine Inc.]]</div>Prab