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<p><b>New page</b></p><div>[[File:Lesopitron.png|thumb|{{PAGENAME}}]]<br>'''Lesopitron''' is a [[selective serotonin receptor antagonist]] developed by [[Esteve]]. It is an [[anxiolytic]] drug of the [[azapirone]] class, similar to other azapirones like [[buspirone]] and [[ipsapirone]].<br />
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==Pharmacology==<br />
Lesopitron acts as a [[5-HT1A receptor]] antagonist. The 5-HT1A receptor is a subtype of the [[5-HT receptor]] that binds the [[neurotransmitter]] [[serotonin]], and is prevalent in the [[cerebral cortex]], [[hippocampus]], [[septum]], [[amygdala]], and [[raphe nucleus]], all of which are areas associated with [[anxiety]] and [[depression]].<br />
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==Clinical Use==<br />
Lesopitron is primarily used in the treatment of [[generalized anxiety disorder]] (GAD). It has been shown to have similar efficacy to [[benzodiazepines]] in treating GAD, but with fewer side effects such as sedation and dependency.<br />
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==Side Effects==<br />
Common side effects of Lesopitron include dizziness, nausea, and headache. Less common side effects can include dry mouth, constipation, and changes in weight. As with all medications, it is important to monitor for any unusual or severe side effects and report them to a healthcare provider.<br />
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==See Also==<br />
* [[5-HT1A receptor]]<br />
* [[Anxiolytic]]<br />
* [[Azapirone]]<br />
* [[Buspirone]]<br />
* [[Ipsapirone]]<br />
* [[Serotonin]]<br />
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[[Category:Drugs]]<br />
[[Category:Anxiolytics]]<br />
[[Category:Azapirones]]<br />
{{Pharmacology-stub}}<br />
{{Serotonin receptor antagonists}}<br />
{{Anxiolytics}}</div>Prab