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	<title>LPAR3 - Revision history</title>
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	<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=LPAR3&amp;action=history"/>
	<updated>2026-04-24T12:16:45Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=LPAR3&amp;diff=6511606&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=LPAR3&amp;diff=6511606&amp;oldid=prev"/>
		<updated>2025-03-17T16:44:09Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:44, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l21&quot;&gt;Line 21:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=LPAR3&amp;diff=6271224&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=LPAR3&amp;diff=6271224&amp;oldid=prev"/>
		<updated>2025-02-11T03:06:48Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 03:06, 11 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l20&quot;&gt;Line 20:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 20:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{Human chromosome 1 gene stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{Human chromosome 1 gene stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=LPAR3&amp;diff=5379645&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=LPAR3&amp;diff=5379645&amp;oldid=prev"/>
		<updated>2024-03-10T06:39:07Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;LPAR3&amp;#039;&amp;#039;&amp;#039; or &amp;#039;&amp;#039;&amp;#039;Lysophosphatidic Acid Receptor 3&amp;#039;&amp;#039;&amp;#039; is a [[protein]] that in humans is encoded by the LPAR3 [[gene]]. It is a member of the [[G protein-coupled receptor]] family and plays a crucial role in several [[biological process]]es, including [[cell proliferation]], [[cell differentiation]], and [[apoptosis]].&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
LPAR3 is a receptor for [[lysophosphatidic acid]] (LPA), a [[bioactive lipid]] mediator that influences various biological functions. LPA receptors are involved in many physiological and pathological processes, including [[embryo implantation]], [[cell migration]], [[neurogenesis]], and [[cancer metastasis]]. LPAR3, in particular, has been implicated in the regulation of [[immune response]]s and [[inflammation]].&lt;br /&gt;
&lt;br /&gt;
== Structure ==&lt;br /&gt;
The LPAR3 protein is a seven-transmembrane receptor, characteristic of the G protein-coupled receptor family. It is primarily located on the [[cell membrane]], where it interacts with its ligand, LPA.&lt;br /&gt;
&lt;br /&gt;
== Clinical Significance ==&lt;br /&gt;
Alterations in the LPAR3 gene have been associated with several diseases, including [[ovarian cancer]], [[asthma]], and [[rheumatoid arthritis]]. In ovarian cancer, overexpression of LPAR3 has been linked to increased tumor aggressiveness and poor prognosis. In asthma and rheumatoid arthritis, variations in the LPAR3 gene may influence disease susceptibility and severity.&lt;br /&gt;
&lt;br /&gt;
== Research ==&lt;br /&gt;
Research on LPAR3 is ongoing, with studies focusing on its role in disease progression and potential as a therapeutic target. For example, drugs that block LPAR3 activity may be useful in treating conditions like ovarian cancer and inflammatory diseases.&lt;br /&gt;
&lt;br /&gt;
[[Category:G protein-coupled receptors]]&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:Genes on human chromosome 1]]&lt;br /&gt;
&lt;br /&gt;
{{G protein-coupled receptors}}&lt;br /&gt;
{{Human chromosome 1 gene stub}}&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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