Keshan disease - Revision history

Prab: CSV import

2025-04-04T03:05:30Z

CSV import

← Older revision		Revision as of 03:05, 4 April 2025
Line 1:		Line 1:

			{{Infobox medical condition
			\| name = Keshan disease
			\| synonyms =
			\| specialty = [[Cardiology]], [[Endocrinology]]
			\| symptoms = [[Cardiomyopathy]], [[heart failure]], [[arrhythmia]], [[edema]]
			\| complications = [[Heart failure]], [[cardiac arrest]]
			\| onset = Typically in [[children]] and [[women of childbearing age]]
			\| duration = Chronic
			\| causes = [[Selenium deficiency]], [[Coxsackievirus]] infection
			\| risks = Living in selenium-deficient regions, poor diet
			\| diagnosis = [[Clinical diagnosis]], [[Echocardiogram]], [[Electrocardiogram]]
			\| differential = [[Dilated cardiomyopathy]], [[Myocarditis]]
			\| prevention = [[Selenium supplementation]]
			\| treatment = [[Selenium supplementation]], [[supportive care]]
			\| prognosis = Variable, can be severe if untreated
			\| frequency = Endemic in certain regions of [[China]]
			}}
	Keshan disease is disease caused by selenium deficiency in combination with a second stress (possibly a viral infection).		Keshan disease is disease caused by selenium deficiency in combination with a second stress (possibly a viral infection).
	<youtube>		<youtube>

Prab at 12:56, 18 March 2025

2025-03-18T12:56:15Z

← Older revision		Revision as of 12:56, 18 March 2025
Line 55:		Line 55:
	[[Category:Mineral deficiencies]]		[[Category:Mineral deficiencies]]
	{{No image}}		{{No image}}
	~~__NOINDEX__~~

Prab: CSV import

2025-03-17T16:31:32Z

CSV import

← Older revision		Revision as of 16:31, 17 March 2025
Line 55:		Line 55:
	[[Category:Mineral deficiencies]]		[[Category:Mineral deficiencies]]
	{{No image}}		{{No image}}
			__NOINDEX__

Prab: CSV import

2025-02-11T00:32:06Z

CSV import

← Older revision		Revision as of 00:32, 11 February 2025
Line 54:		Line 54:
	[[Category:Heart diseases]]		[[Category:Heart diseases]]
	[[Category:Mineral deficiencies]]		[[Category:Mineral deficiencies]]
			{{No image}}

Prab at 14:41, 29 April 2022

2022-04-29T14:41:16Z

New page

Keshan disease is disease caused by selenium deficiency in combination with a second stress (possibly a viral infection).
<youtube>
title='''{{PAGENAME}}'''
movie_url=http://www.youtube.com/v/5uZlfK5L0bk
&rel=1
embed_source_url=http://www.youtube.com/v/5uZlfK5L0bk
&rel=1
wrap = yes
width=750
height=600
</youtube>
==Role of selenium==
* Selenium an element that the body needs to function properly.
* The patients are also[[Selenium]] is an important component of [[selenoproteins]], such as [[selenoprotein P]], [[deiodinase]], and [[GPx]] enzymes
==Epidemiology==
Keshan disease (KD) is an endemic cardiomyopathy first reported in [[Keshan County]] in [[China]] in 1935.
==Chinese supplementation==
Before the Chinese government selenium supplementation program in the 1970's, adults in the Keshan disease areas had average selenium intakes of no more than 11 mcg/day; intakes of at least 20 mcg/day protect adults from Keshan disease.
==Signs and symptoms==
The clinical manifestations of KD are acute or chronic episodes of heart disease characterized by the following signs and symptoms:
* [[cardiogenic shock]],
* ppcongestive heart failure[[,
* [[arrhythmia]],
* [[cardiomegaly]]
==Types==
Based on the presentation and onset of symptoms, the following four types are described:
# acute KD,
# subacute KD,
# chronic KD, and
# latent KD.
==Diagnosis==
Diagnosis is based on a combination of blood tests including [[selenium]] levels, [[EKG]], [[echocardiography]] etc.
==Treatment==
The treatment for Keshan disease is supportive care for the heart failure, and low dose [[selenium supplementation]].
==Sources of selenium==
* [[Brazil nuts]], [[seafood]]s, and [[organ meats]] are the richest food sources of selenium
* Other sources include muscle meats, cereals and other grains, and dairy products
* The amount of selenium in drinking water is not nutritionally significant in most geographic regions
* The major food sources of selenium in the American diet are [[breads]], [[grains]], [[meat]], [[poultry]], [[fish]], and [[eggs]].
==Dose==
'''The recommended amounts are'''
* 55 micrograms of selenium per day for adult men and women,
* 60 micrograms a day for women during pregnancy and
* 70 micrograms per day for women after pregnancy
==Dietary supplementation==
* Selenium is available in multivitamin/multimineral supplements and as a stand-alone supplement, often in the forms of selenomethionine or of selenium-enriched yeast (grown in a high-selenium medium) or as sodium selenite or sodium selenate.
* The human body absorbs more than 90% of selenomethionine but only about 50% of selenium from selenite
==Other diseases==
* Selenium deficiency is also associated with male infertility and might play a role in [[Kashin-Beck disease]], a type of [[osteoarthritis]] that occurs in certain low-selenium areas of [[China]], [[Tibet]], and [[Siberia]].
* Selenium deficiency could exacerbate [[iodine deficiency]], potentially increasing the risk of [[cretinism]] in infant
{{stub}}
{{Nutritional pathology}}
{{Heart diseases}}
[[Category:Heart diseases]]
[[Category:Mineral deficiencies]]