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	<title>KCNJ12 - Revision history</title>
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	<updated>2026-04-22T01:45:18Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=KCNJ12&amp;diff=6511219&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=KCNJ12&amp;diff=6511219&amp;oldid=prev"/>
		<updated>2025-03-17T16:15:41Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:15, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=KCNJ12&amp;diff=6270562&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=KCNJ12&amp;diff=6270562&amp;oldid=prev"/>
		<updated>2025-02-11T02:32:00Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 02:32, 11 February 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=KCNJ12&amp;diff=5378725&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=KCNJ12&amp;diff=5378725&amp;oldid=prev"/>
		<updated>2024-03-10T05:33:02Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;KCNJ12&amp;#039;&amp;#039;&amp;#039; is a gene that encodes the protein Kir2.2, a member of the [[Inward-rectifier potassium ion channels|inward-rectifier potassium ion channel]] family. This protein plays a crucial role in maintaining the [[Resting membrane potential|resting membrane potential]] and the regulation of the [[Action potential|action potentials]] in neurons and muscle cells. &lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
The KCNJ12 gene provides instructions for making a protein that forms a channel, which allows [[Potassium|potassium ions]] to flow into cells. This flow of ions is critical for maintaining the normal function of [[Muscle cells|muscle cells]], including those in the heart. The protein produced from the KCNJ12 gene is found in the [[Cell membrane|cell membrane]] and is particularly abundant in the heart and brain.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
Mutations in the KCNJ12 gene have been associated with certain types of [[Cardiac arrhythmia|cardiac arrhythmias]], including [[Andersen-Tawil syndrome|Andersen-Tawil Syndrome]] and [[Short QT syndrome|Short QT Syndrome]]. These conditions can cause life-threatening irregular heartbeats, fainting spells, and even sudden death. &lt;br /&gt;
&lt;br /&gt;
== Research ==&lt;br /&gt;
Research is ongoing to better understand the role of the KCNJ12 gene and its associated protein in health and disease. This includes studies to identify additional mutations that may cause cardiac arrhythmias and to develop new treatments for these conditions.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Inward-rectifier potassium ion channels]]&lt;br /&gt;
* [[Resting membrane potential]]&lt;br /&gt;
* [[Action potential]]&lt;br /&gt;
* [[Potassium]]&lt;br /&gt;
* [[Muscle cells]]&lt;br /&gt;
* [[Cell membrane]]&lt;br /&gt;
* [[Cardiac arrhythmia]]&lt;br /&gt;
* [[Andersen-Tawil syndrome]]&lt;br /&gt;
* [[Short QT syndrome]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
[[Category:Ion channels]]&lt;br /&gt;
[[Category:Cardiology]]&lt;br /&gt;
[[Category:Neurology]]&lt;br /&gt;
&lt;br /&gt;
{{Genes on human chromosome 17}}&lt;br /&gt;
{{Ion channels}}&lt;br /&gt;
{{Cardiology}}&lt;br /&gt;
{{Neurology}}&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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