https://wikimd.com/index.php?action=history&feed=atom&title=JAM2 JAM2 - Revision history 2026-04-09T01:49:50Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=JAM2&diff=6510698&oldid=prev Prab: CSV import 2025-03-17T15:37:41Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:37, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=JAM2&diff=6270619&oldid=prev Prab: CSV import 2025-02-11T02:34:18Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:34, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=JAM2&diff=5379274&oldid=prev Prab: CSV import 2024-03-10T06:12:51Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;JAM2&#039;&#039;&#039; or &#039;&#039;&#039;Junctional Adhesion Molecule 2&#039;&#039;&#039; is a [[protein]] that in humans is encoded by the JAM2 [[gene]]. It is a member of the [[immunoglobulin superfamily]] and is involved in various [[cellular processes]] such as [[cell adhesion]] and [[cell migration]].<br /> <br /> == Function ==<br /> JAM2 is a type of [[cell adhesion molecule]] (CAM) that is expressed on the surface of [[leukocytes]] and [[endothelial cells]]. It plays a crucial role in the [[immune response]] by facilitating the migration of leukocytes across the [[endothelium]], a layer of cells that forms the inner lining of [[blood vessels]] and [[lymphatic vessels]]. This process is known as [[leukocyte transmigration]].<br /> <br /> == Structure ==<br /> The JAM2 protein is composed of two [[extracellular]] [[immunoglobulin]] domains, a single [[transmembrane domain]], and a short [[cytoplasmic]] tail. The extracellular domains are involved in the binding of JAM2 to its [[ligand]], while the cytoplasmic tail interacts with [[cytoskeletal]] proteins and [[signaling molecules]].<br /> <br /> == Clinical significance ==<br /> Mutations in the JAM2 gene have been associated with various [[disease]]s, including [[inflammatory diseases]] and [[cancer]]. In particular, overexpression of JAM2 has been observed in certain types of [[leukemia]] and [[lymphoma]], suggesting a potential role in [[tumor progression]].<br /> <br /> == Research ==<br /> Research on JAM2 is ongoing, with studies focusing on its role in [[immune response]], [[inflammation]], and [[cancer progression]]. Understanding the function of JAM2 could potentially lead to the development of new [[therapeutic]] strategies for treating diseases associated with abnormal cell adhesion and migration.<br /> <br /> == See also ==<br /> * [[Junctional adhesion molecule]]<br /> * [[Cell adhesion molecule]]<br /> * [[Leukocyte transmigration]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Proteins]]<br /> [[Category:Cell adhesion molecules]]<br /> [[Category:Immunoglobulin superfamily]]<br /> [[Category:Genes]]<br /> [[Category:Medicine]]<br /> <br /> {{medicine-stub}}</div> Prab