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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Isonipecotic_acid</id>
	<title>Isonipecotic acid - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Isonipecotic_acid"/>
	<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Isonipecotic_acid&amp;action=history"/>
	<updated>2026-04-27T05:56:24Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.44.2</generator>
	<entry>
		<id>https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=6528743&amp;oldid=prev</id>
		<title>Prab at 17:28, 18 March 2025</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=6528743&amp;oldid=prev"/>
		<updated>2025-03-18T17:28:55Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 17:28, 18 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l29&quot;&gt;Line 29:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=6510506&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=6510506&amp;oldid=prev"/>
		<updated>2025-03-17T15:28:09Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:28, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l29&quot;&gt;Line 29:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 29:&lt;/td&gt;&lt;/tr&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{No image}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{No image}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=6270007&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=6270007&amp;oldid=prev"/>
		<updated>2025-02-11T02:07:58Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 02:07, 11 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l28&quot;&gt;Line 28:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 28:&lt;/td&gt;&lt;/tr&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{No image}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=5330592&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Isonipecotic_acid&amp;diff=5330592&amp;oldid=prev"/>
		<updated>2024-02-29T04:15:32Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Isonipecotic acid&amp;#039;&amp;#039;&amp;#039; is an [[organic compound]] with the formula C6H11NO2. It is a [[carboxylic acid]] that contains a [[pyrrolidine]] ring, and is a structural isomer of [[nipecotic acid]]. Isonipecotic acid is used in the synthesis of various pharmaceuticals, including some [[antiepileptic drugs]].&lt;br /&gt;
&lt;br /&gt;
== Structure and properties ==&lt;br /&gt;
&lt;br /&gt;
Isonipecotic acid consists of a five-membered pyrrolidine ring, which contains a [[nitrogen]] atom, and a carboxylic acid group. The presence of the nitrogen atom makes the compound a [[heterocycle]]. The carboxylic acid group can participate in [[hydrogen bonding]], which can affect the compound&amp;#039;s physical properties and reactivity.&lt;br /&gt;
&lt;br /&gt;
== Synthesis ==&lt;br /&gt;
&lt;br /&gt;
Isonipecotic acid can be synthesized from [[glutaric acid]] or its derivatives, in a process that involves the formation of a [[cyclic compound]] and subsequent [[functional group]] transformations.&lt;br /&gt;
&lt;br /&gt;
== Applications ==&lt;br /&gt;
&lt;br /&gt;
Isonipecotic acid is used as a building block in the synthesis of various pharmaceuticals. For example, it is used in the synthesis of [[vigabatrin]], an antiepileptic drug. The compound&amp;#039;s pyrrolidine ring can act as a [[bioisostere]] for the [[gamma-aminobutyric acid|GABA]] neurotransmitter, which can enhance the activity of GABA in the brain and help to control seizures.&lt;br /&gt;
&lt;br /&gt;
== Safety ==&lt;br /&gt;
&lt;br /&gt;
As with all chemicals, isonipecotic acid should be handled with care. It can cause skin and eye irritation, and may be harmful if swallowed or inhaled.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
&lt;br /&gt;
* [[Pyrrolidine]]&lt;br /&gt;
* [[Nipecotic acid]]&lt;br /&gt;
* [[Vigabatrin]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Carboxylic acids]]&lt;br /&gt;
[[Category:Heterocyclic compounds]]&lt;br /&gt;
[[Category:Pharmaceutical chemistry]]&lt;br /&gt;
{{Chem-stub}}&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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