https://wikimd.com/index.php?action=history&feed=atom&title=Internal_limiting_membraneInternal limiting membrane - Revision history2026-04-22T09:49:59ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.com/index.php?title=Internal_limiting_membrane&diff=6305090&oldid=prevPrab: CSV import2025-02-17T01:48:53Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Internal limiting membrane''' ('''ILM''') is the innermost layer of the [[retina]], which separates the vitreous body from the rest of the retina. It is a transparent, acellular structure that plays a crucial role in maintaining the structural and functional integrity of the retina.<br />
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== Structure ==<br />
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The ILM is composed of two main components: the basement membrane of the [[Müller cells]] and the footplates of the [[astrocytes]]. The basement membrane of the Müller cells forms the bulk of the ILM, while the astrocytes provide additional support and stability.<br />
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== Function ==<br />
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The primary function of the ILM is to provide a barrier between the vitreous body and the rest of the retina. This barrier prevents the migration of cells and molecules from the vitreous body into the retina, thereby maintaining the structural and functional integrity of the retina. The ILM also plays a role in the regulation of [[retinal blood flow]] and the transport of nutrients and waste products between the retina and the vitreous body.<br />
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== Clinical significance ==<br />
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In certain pathological conditions, such as [[macular hole]] and [[epiretinal membrane]], the ILM can become thickened or contracted, leading to visual impairment. Surgical removal of the ILM (ILM peeling) is a common treatment for these conditions. However, this procedure can be challenging due to the thin and transparent nature of the ILM.<br />
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== See also ==<br />
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* [[Retina]]<br />
* [[Müller cells]]<br />
* [[Astrocytes]]<br />
* [[Macular hole]]<br />
* [[Epiretinal membrane]]<br />
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== References ==<br />
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{{reflist}}<br />
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[[Category:Eye anatomy]]<br />
[[Category:Retina]]<br />
{{Eye-stub}}</div>Prab