https://wikimd.com/index.php?action=history&feed=atom&title=Interleukin_37 2026-04-24T05:52:27Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Interleukin_37&diff=6510140&oldid=prev 2025-03-17T15:07:22Z

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Prab https://wikimd.com/index.php?title=Interleukin_37&diff=5330454&oldid=prev 2024-02-29T04:07:30Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Interleukin 37&#039;&#039;&#039; (&#039;&#039;&#039;IL-37&#039;&#039;&#039;) is a member of the [[interleukin]] family, which is a group of [[cytokines]] that play a crucial role in the [[immune system]]. IL-37 is known for its anti-inflammatory properties and is involved in various biological processes.<br /> <br /> == Structure ==<br /> IL-37 is a protein that is encoded by the IL37 gene in humans. It is a member of the IL-1 family and shares similar gene structure. The IL37 gene is located on [[chromosome 2]] and consists of 6 exons. The protein product is a precursor protein that is processed into its active form by [[caspase-1]].<br /> <br /> == Function ==<br /> IL-37 is primarily known for its anti-inflammatory role. It is produced by immune cells in response to inflammatory stimuli and acts to suppress the immune response. This is achieved by inhibiting the production of pro-inflammatory cytokines and enhancing the production of anti-inflammatory cytokines. IL-37 can also induce the production of [[regulatory T cells]], further contributing to its anti-inflammatory effects.<br /> <br /> == Clinical significance ==<br /> Due to its anti-inflammatory properties, IL-37 has been implicated in a number of diseases. High levels of IL-37 have been found in patients with [[autoimmune diseases]], such as [[rheumatoid arthritis]] and [[systemic lupus erythematosus]]. It has also been associated with [[cancer]], with studies showing that IL-37 can inhibit tumor growth and metastasis.<br /> <br /> == Research ==<br /> Research into IL-37 is ongoing, with studies aiming to further understand its role in the immune system and its potential as a therapeutic target. Current research is focused on understanding the mechanisms by which IL-37 exerts its anti-inflammatory effects and how these can be harnessed for the treatment of inflammatory and autoimmune diseases.<br /> <br /> == See also ==<br /> * [[Interleukin]]<br /> * [[Cytokine]]<br /> * [[Immune system]]<br /> * [[Autoimmune disease]]<br /> * [[Cancer]]<br /> <br /> [[Category:Interleukins]]<br /> [[Category:Cytokines]]<br /> [[Category:Immune system]]<br /> [[Category:Autoimmune diseases]]<br /> [[Category:Cancer]]<br /> <br /> {{medicine-stub}}</div>

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