https://wikimd.com/index.php?action=history&feed=atom&title=Interleukin_20_receptor%2C_beta_subunitInterleukin 20 receptor, beta subunit - Revision history2026-04-16T12:20:56ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.com/index.php?title=Interleukin_20_receptor,_beta_subunit&diff=5329600&oldid=prevPrab: CSV import2024-02-29T03:19:22Z<p>CSV import</p>
<p><b>New page</b></p><div>'''Interleukin 20 receptor, beta subunit''' (IL20RB) is a [[protein]] that in humans is encoded by the ''IL20RB'' [[gene]]. This protein is a part of the [[interleukin receptor]] family, which plays a crucial role in the [[immune system]]'s response to various diseases and infections.<br />
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== Function ==<br />
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The IL20RB protein is a subunit of the interleukin 20 receptor complex, which also includes the [[Interleukin 20 receptor, alpha subunit|alpha subunit]]. This complex binds to [[interleukin 20]] (IL20), [[interleukin 19]] (IL19), and [[interleukin 24]] (IL24). Upon binding, the receptor complex activates intracellular signaling pathways that lead to the expression of genes involved in [[inflammation]], [[cell proliferation]], and [[cell differentiation]].<br />
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== Clinical significance ==<br />
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Mutations in the ''IL20RB'' gene have been associated with various diseases, including [[psoriasis]], [[rheumatoid arthritis]], and [[cancer]]. In particular, overexpression of IL20RB has been observed in several types of cancer, suggesting a potential role in [[tumor]] growth and progression.<br />
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== See also ==<br />
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* [[Interleukin 20 receptor, alpha subunit]]<br />
* [[Interleukin 20]]<br />
* [[Interleukin 19]]<br />
* [[Interleukin 24]]<br />
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== References ==<br />
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{{Reflist}}<br />
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[[Category:Interleukin receptors]]<br />
[[Category:Human proteins]]<br />
[[Category:Immune system]]<br />
{{protein-stub}}<br />
{{medicine-stub}}</div>Prab