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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Insulin-like_growth_factor</id>
	<title>Insulin-like growth factor - Revision history</title>
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	<updated>2026-04-30T06:19:24Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=Insulin-like_growth_factor&amp;diff=6304742&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Insulin-like_growth_factor&amp;diff=6304742&amp;oldid=prev"/>
		<updated>2025-02-17T01:01:54Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 01:01, 17 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l28&quot;&gt;Line 28:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Insulin-like growth factor ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;gallery&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;File:3GF1_Insulin-Like_Growth_Factor_Nmr_10_01.png&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Insulin-like_growth_factor&amp;diff=5258965&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Insulin-like_growth_factor&amp;diff=5258965&amp;oldid=prev"/>
		<updated>2024-02-24T05:23:53Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Insulin-like growth factor&amp;#039;&amp;#039;&amp;#039; (IGF), also known as &amp;#039;&amp;#039;&amp;#039;somatomedin&amp;#039;&amp;#039;&amp;#039;, is a protein that has a similar molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. &lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
IGF is produced by the liver as an endocrine hormone as well as by target tissues in a paracrine/autocrine fashion. Production is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signaling pathway post GH receptor including SHP2 and STAT5B. &lt;br /&gt;
&lt;br /&gt;
== Types ==&lt;br /&gt;
There are two types of IGF, namely [[IGF-1]] and [[IGF-2]]. IGF-1 is primarily responsible for the long bone growth in children and it also affects muscle growth and repair of adults. IGF-2 is a major fetal growth factor.&lt;br /&gt;
&lt;br /&gt;
== Role in disease ==&lt;br /&gt;
IGF is implicated in several diseases. It is suspected to play a role in cancer, as it can lead to increased proliferation and inhibition of apoptosis. It also can increase the production of [[angiogenesis]] factors and metastasis.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Insulin]]&lt;br /&gt;
* [[Growth hormone]]&lt;br /&gt;
* [[Diabetes mellitus]]&lt;br /&gt;
* [[Cancer]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001393/ Insulin-like growth factor] at PubMed Health&lt;br /&gt;
&lt;br /&gt;
[[Category:Proteins]]&lt;br /&gt;
[[Category:Hormones]]&lt;br /&gt;
[[Category:Endocrinology]]&lt;br /&gt;
[[Category:Growth factors]]&lt;br /&gt;
{{stub}}&lt;br /&gt;
{{dictionary-stub1}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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