https://wikimd.org/index.php?action=history&feed=atom&title=Immunoconjugate Immunoconjugate - Revision history 2026-04-26T14:16:38Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Immunoconjugate&diff=6524405&oldid=prev Prab at 12:49, 18 March 2025 2025-03-18T12:49:58Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:49, 18 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l32">Line 32:</td> <td colspan="2" class="diff-lineno">Line 32:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; 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white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=Immunoconjugate&diff=5258361&oldid=prev Prab: CSV import 2024-02-24T04:53:03Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Immunoconjugate&#039;&#039;&#039; is a type of [[biological therapy]] that combines a [[monoclonal antibody]] with a [[cytotoxic drug]] or a [[radioactive particle]]. The monoclonal antibody binds to specific [[proteins]] or [[antigens]] on [[cancer cells]], delivering the cytotoxic drug or radioactive particle directly to the cancer, which may help decrease damage to healthy cells. Immunoconjugates are used in the treatment of certain types of [[cancer]].<br /> <br /> ==Overview==<br /> [[Monoclonal antibodies]] are laboratory-produced molecules that can locate and bind to cancer cells wherever they are in the body. They can be used alone, or they can be used to deliver drugs, toxins, or radioactive material directly to tumor cells.<br /> <br /> An &#039;&#039;&#039;immunoconjugate&#039;&#039;&#039; is a complex of an antibody (or an antibody fragment) linked to a second molecule, which might be a [[chemotherapeutic agent]], a [[toxin]], or a [[radioactive compound]]. The antibody binds to specific antigens on the surface of the cell, delivering the second molecule to the cell.<br /> <br /> ==Types of Immunoconjugates==<br /> There are several types of immunoconjugates, including [[Antibody-drug conjugates]] (ADCs), [[Radioimmunotherapy]] (RIT) agents, and [[Immunotoxins]].<br /> <br /> ===Antibody-Drug Conjugates===<br /> [[Antibody-drug conjugates]] (ADCs) are monoclonal antibodies (mAbs) attached to biologically active drugs. By combining the unique targeting of mAbs with the cancer-killing ability of cytotoxic drugs, ADCs allow sensitive discrimination between healthy and diseased tissue.<br /> <br /> ===Radioimmunotherapy===<br /> [[Radioimmunotherapy]] (RIT) involves the use of radioactively conjugated murine antibodies against cellular antigens. RIT allows targeted delivery of radiation to the cancer cells.<br /> <br /> ===Immunotoxins===<br /> [[Immunotoxins]] are a group of protein-based therapeutics composed of a targeting moiety linked to a toxin. The targeting moiety is usually a monoclonal antibody that recognizes and binds to specific cell surface antigens.<br /> <br /> ==Clinical Applications==<br /> Immunoconjugates have been used in the treatment of various types of cancers, including [[breast cancer]], [[lymphoma]], and [[leukemia]]. They have shown promise in clinical trials, with some immunoconjugates being approved for use by the [[Food and Drug Administration]] (FDA).<br /> <br /> ==See Also==<br /> * [[Monoclonal antibodies]]<br /> * [[Cancer treatment]]<br /> * [[Chemotherapy]]<br /> * [[Radiotherapy]]<br /> <br /> [[Category:Medical Terms]]<br /> [[Category:Cancer Treatment]]<br /> [[Category:Biological Therapy]]<br /> {{stub}}</div> Prab