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	<title>INHBB - Revision history</title>
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	<updated>2026-04-24T15:24:36Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=INHBB&amp;diff=6509440&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=INHBB&amp;diff=6509440&amp;oldid=prev"/>
		<updated>2025-03-17T14:28:23Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 14:28, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l25&quot;&gt;Line 25:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=INHBB&amp;diff=6264524&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
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		<updated>2025-02-10T23:52:20Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:52, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l24&quot;&gt;Line 24:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=INHBB&amp;diff=5378781&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
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		<updated>2024-03-10T05:36:46Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;INHBB&amp;#039;&amp;#039;&amp;#039; is a gene that encodes the inhibin beta B subunit in humans. This protein is a subunit of both [[activin]] and [[inhibin]], two closely related glycoproteins with opposing biological effects.&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
The &amp;#039;&amp;#039;&amp;#039;INHBB&amp;#039;&amp;#039;&amp;#039; gene is a member of the [[transforming growth factor beta]] (TGF-beta) superfamily. The encoded protein is synthesized as a large precursor molecule that is cleaved to form a 12 kDa mature protein subunit and a 26 kDa [[N-terminal propeptide]]. This protein subunit can form homodimers or can be paired with the beta A subunit to form a heterodimer, both of which are active in inhibin and activin complexes.&lt;br /&gt;
&lt;br /&gt;
The bioactive complex of inhibin B (alpha and beta B subunit) acts as a negative feedback regulator of [[follicle-stimulating hormone]] (FSH) secretion. On the other hand, the activin complex (beta B homodimer) stimulates FSH secretion. Therefore, the balance of inhibin B and activin secretion regulates FSH secretion and, consequently, reproductive function.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
&lt;br /&gt;
Mutations in the &amp;#039;&amp;#039;&amp;#039;INHBB&amp;#039;&amp;#039;&amp;#039; gene are associated with [[premature ovarian failure]] and [[polycystic ovary syndrome]]. In addition, elevated levels of inhibin B are found in individuals with [[granulosa cell tumors]] and are used as a tumor marker in clinical tests.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Inhibin]]&lt;br /&gt;
* [[Activin]]&lt;br /&gt;
* [[Follicle-stimulating hormone]]&lt;br /&gt;
* [[Transforming growth factor beta]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:Endocrinology]]&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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