https://wikimd.com/index.php?action=history&feed=atom&title=IGFBP1 IGFBP1 - Revision history 2026-04-21T23:06:10Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=IGFBP1&diff=6509851&oldid=prev Prab: CSV import 2025-03-17T14:50:33Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 14:50, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l32">Line 32:</td> <td colspan="2" class="diff-lineno">Line 32:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> <!-- diff cache key wikimd4:diff:1.41:old-6254693:rev-6509851:php=table --> </table> Prab https://wikimd.com/index.php?title=IGFBP1&diff=6254693&oldid=prev Prab: CSV import 2025-02-10T20:28:32Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:28, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l31">Line 31:</td> <td colspan="2" class="diff-lineno">Line 31:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Protein-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Protein-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=IGFBP1&diff=5325925&oldid=prev Prab: CSV import 2024-02-28T21:01:07Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;IGFBP1&#039;&#039;&#039; (Insulin-like Growth Factor Binding Protein 1) is a protein that in humans is encoded by the IGFBP1 gene. It is one of six binding proteins (IGFBP1-6) that have high affinity for [[Insulin-like Growth Factors]] (IGFs). <br /> <br /> == Function ==<br /> IGFBP1 is a secreted protein that binds to both [[Insulin-like Growth Factor 1|IGF-I]] and [[Insulin-like Growth Factor 2|IGF-II]] with high affinity. The binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP1 is expressed in many tissues, including liver, brain, heart, and kidneys. It plays a crucial role in regulating IGF bioavailability, and thus, cell growth and survival.<br /> <br /> == Clinical Significance ==<br /> Alterations in the serum concentration of IGFBP1 have been associated with a variety of diseases. High levels of IGFBP1 have been observed in conditions such as [[Type 1 Diabetes]], [[Fasting]], and [[Physical Exercise]]. Conversely, low levels of IGFBP1 are associated with [[Type 2 Diabetes]], [[Insulin Resistance]], and [[Obesity]]. <br /> <br /> In addition, IGFBP1 has been implicated in the development and progression of several types of cancer, including [[Breast Cancer]], [[Prostate Cancer]], and [[Colorectal Cancer]]. It is thought that IGFBP1 may influence cancer cell growth and survival by modulating the bioavailability of IGFs.<br /> <br /> == Research ==<br /> Research into IGFBP1 has focused on understanding its role in health and disease, and its potential as a therapeutic target. Studies have investigated the regulation of IGFBP1 expression, its interaction with IGFs and IGF receptors, and its effects on cell growth and survival. <br /> <br /> == See Also ==<br /> * [[Insulin-like Growth Factor]]<br /> * [[Insulin-like Growth Factor 1]]<br /> * [[Insulin-like Growth Factor 2]]<br /> * [[Insulin Resistance]]<br /> * [[Type 1 Diabetes]]<br /> * [[Type 2 Diabetes]]<br /> * [[Breast Cancer]]<br /> * [[Prostate Cancer]]<br /> * [[Colorectal Cancer]]<br /> <br /> [[Category:Proteins]]<br /> [[Category:Human Proteins]]<br /> [[Category:Growth Factors]]<br /> [[Category:Diabetes]]<br /> [[Category:Cancer]]<br /> <br /> {{Protein-stub}}<br /> {{Medicine-stub}}</div> Prab