Prab at 18:35, 18 March 2025

2025-03-18T18:35:17Z

← Older revision		Revision as of 18:35, 18 March 2025
Line 33:		Line 33:
	{{rarediseases}}		{{rarediseases}}
	{{stub}}		{{stub}}
	~~__NOINDEX__~~

Prab: CSV import

2025-02-04T08:32:21Z

CSV import

← Older revision		Revision as of 08:32, 4 February 2025
Line 33:		Line 33:
	{{rarediseases}}		{{rarediseases}}
	{{stub}}		{{stub}}
			__NOINDEX__

Deepika vegiraju: Created page with "== '''Alternate names''' == Trembling chin; GSM 1; Hereditary chin tremor/myoclonus; Geniospasm == '''Definition''' == Hereditary geniospasm is a movement disorder that cause..."

2021-03-25T17:37:40Z

Created page with "== '''Alternate names''' == Trembling chin; GSM 1; Hereditary chin tremor/myoclonus; Geniospasm == '''Definition''' == Hereditary geniospasm is a movement disorder that cause..."

New page

== '''Alternate names''' ==
Trembling chin; GSM 1; Hereditary chin tremor/myoclonus; Geniospasm

== '''Definition''' ==
Hereditary geniospasm is a movement disorder that causes episodes of involuntary [[tremors]] of the chin and lower lip.

== '''Cause''' ==
Although the exact gene that causes the condition is unknown, it has been suggested that mutations in a gene on '''chromosome 9''' may be responsible in some families.

== '''Inheritance''' ==
[[File:Autosomal dominant - en.svg|thumb|right|Autosomal dominant pattern, a 50/50 chance.]]
* Hereditary geniospasm is inherited in an [[autosomal dominant]] manner.
* This means that having only one mutated copy of the causative gene in each body cell is sufficient to cause signs and symptoms of the condition.
* When an individual with an autosomal dominant condition has children, each child has a 50% (1 in 2) chance to inherit the mutated copy of the gene and also be affected.
* Because there is a 50% chance for each child, it is possible for all of the children of an affected individual to be affected, or likewise, for all of the children to be unaffected.

== '''Signs and symptoms''' ==
* It is a movement disorder that causes episodes of involuntary [[tremors]] of the chin and lower lip.
* The episodes may last anywhere from a few seconds to hours and may occur spontaneously or be brought on by [[stress]].
* The episodes usually first appear in infancy or childhood and tend to lessen in frequency with age.

== '''Diagnosis''' ==
The condition can be diagnosed on the basis of a clinical evaluation performed by a health care professional such as a [[neurologist]] who specializes in movement disorders.

== '''Treatment''' ==
* Hereditary geniospasm, which may also be referred to as hereditary essential chin myoclonus, is generally considered a benign disorder although in some cases it can cause [[anxiety]] and social embarrassment.
* Significant improvement with age has been reported.
* Several drugs are used to treat myoclonus, such as [[benzodiazepines]] and [[anticonvulsants]].
* However, individuals may not respond to a single medication and may experience significant side effects if a combination of drugs is used.
* It has also been suggested that [[botulinum toxin]] be considered as a primary treatment because it has been shown to be effective and well tolerated.

[[Category:Neurological disorders]]
{{rarediseases}}
{{stub}}

Hereditary geniospasm - Revision history

Prab at 18:35, 18 March 2025

Prab: CSV import

Deepika vegiraju: Created page with "== '''Alternate names''' == Trembling chin; GSM 1; Hereditary chin tremor/myoclonus; Geniospasm == '''Definition''' == Hereditary geniospasm is a movement disorder that cause..."