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<p><b>New page</b></p><div>'''HOXB5''' is a gene that belongs to the [[homeobox]] family of genes. The [[protein]] encoded by this gene is a [[transcription factor]] that plays a crucial role in [[embryonic development]] and [[cell differentiation]].<br />
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== Function ==<br />
The HOXB5 gene is part of the [[HOX gene]] family, which is a group of genes that play a vital role in the development of the body plan of an organism. The HOXB5 gene, in particular, is involved in the development of the [[respiratory system]] and the [[central nervous system]]. It is also implicated in the development of certain types of [[cancer]].<br />
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== Structure ==<br />
The HOXB5 gene is located on the long (q) arm of [[chromosome 17]] at position 21.32. It spans about 3.2 kilobases and consists of two [[exon]]s. The encoded protein is 253 [[amino acid]]s long.<br />
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== Clinical Significance ==<br />
Mutations in the HOXB5 gene have been associated with various diseases. For instance, it has been linked to [[lung cancer]], [[breast cancer]], and [[leukemia]]. Studies have shown that the overexpression of HOXB5 can lead to the proliferation of cancer cells, suggesting that it may act as an [[oncogene]].<br />
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== Research ==<br />
Research on the HOXB5 gene is ongoing, with scientists aiming to understand its exact role in development and disease. This could potentially lead to the development of new therapeutic strategies for diseases associated with this gene.<br />
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[[Category:Genes]]<br />
[[Category:Human proteins]]<br />
[[Category:Transcription factors]]<br />
[[Category:Oncogenes]]<br />
[[Category:Homeobox genes]]<br />
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