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	<title>HLA-DR8 - Revision history</title>
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	<updated>2026-04-23T17:07:11Z</updated>
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	<entry>
		<id>https://wikimd.com/index.php?title=HLA-DR8&amp;diff=6416688&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
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		<updated>2025-03-03T05:34:27Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 05:34, 3 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l24&quot;&gt;Line 24:&lt;/td&gt;
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		<author><name>Prab</name></author>
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	<entry>
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		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=HLA-DR8&amp;diff=5381543&amp;oldid=prev"/>
		<updated>2024-03-10T12:55:03Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;HLA-DR8&amp;#039;&amp;#039;&amp;#039; is a [[human leukocyte antigen]] serotype within the [[HLA-DR]] serotype group. The serotype is determined by the antibody recognition of [[β-subunit]] of HLA-DR. This β-subunit is encoded by [[HLA-DRB1]] gene and HLA-DR8 is a split antigen of the broad antigen [[HLA-DR3]]. HLA-DR8 and [[HLA-DR53]] are almost always co-expressed.&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
HLA-DR is a cell surface receptor involved in regulating the [[immune system]]. It plays a crucial role in the immune response by presenting [[peptide]]s derived from extracellular proteins to [[T cells]], a type of white blood cell that plays a central role in cell-mediated immunity.&lt;br /&gt;
&lt;br /&gt;
== Association with Diseases ==&lt;br /&gt;
&lt;br /&gt;
HLA-DR8 has been associated with several autoimmune and infectious diseases. These include [[rheumatoid arthritis]], [[multiple sclerosis]], [[type 1 diabetes]], and [[hepatitis B]] infection. However, the exact role of HLA-DR8 in these diseases is not fully understood and is the subject of ongoing research.&lt;br /&gt;
&lt;br /&gt;
== Distribution ==&lt;br /&gt;
&lt;br /&gt;
HLA-DR8 is found at highest frequencies in populations in the Middle East and North Africa. It is also found at significant frequencies in populations in Southern Europe and East Asia.&lt;br /&gt;
&lt;br /&gt;
== See Also ==&lt;br /&gt;
&lt;br /&gt;
* [[HLA-DR]]&lt;br /&gt;
* [[HLA-DRB1]]&lt;br /&gt;
* [[Human leukocyte antigen]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Human leukocyte antigen]]&lt;br /&gt;
[[Category:Immunology]]&lt;br /&gt;
[[Category:Genetics]]&lt;br /&gt;
&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
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