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'''HLA-B54''' is a [[human leukocyte antigen]] (HLA) serotype. The HLA system is a group of genes that play a crucial role in the [[immune system]] function in humans. HLA-B54 is part of the HLA-B locus, a subcategory of HLA class I molecules.

== Function ==

HLA-B54, like other HLA class I molecules, is involved in the presentation of [[peptides]] (small proteins) to the [[T cells]] of the immune system. This process is essential for the immune system to recognize and respond to foreign substances, such as viruses and bacteria.

== Genetics ==

HLA-B54 is encoded by the HLA-B*54 gene allele, a variant form of the HLA-B gene. The HLA-B*54 allele is relatively rare, but it has been identified in certain populations, including some groups in [[Japan]] and [[Korea]].

== Clinical significance ==

HLA-B54 has been associated with a number of medical conditions. For example, it has been linked to a higher risk of [[Hepatitis B]] infection and a lower risk of [[HIV]] progression. However, more research is needed to fully understand these associations and their implications for disease prevention and treatment.

== See also ==

* [[HLA-B]]
* [[Human leukocyte antigen]]
* [[Immune system]]
* [[T cell]]

== References ==

<references />

{{medicine-stub}}

[[Category:Human leukocyte antigen]]
[[Category:Immunology]]
[[Category:Genetics]]

HLA-B54 - Revision history

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