https://wikimd.org/index.php?action=history&feed=atom&title=HER2
HER2 - Revision history
2026-04-27T01:15:06Z
Revision history for this page on the wiki
MediaWiki 1.44.2
https://wikimd.org/index.php?title=HER2&diff=6330470&oldid=prev
Prab: CSV import
2025-02-20T00:36:53Z
<p>CSV import</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 00:36, 20 February 2025</td>
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<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:3D Dual Color Super Resolution Microscopy Cremer 2010.png|HER2</ins></div></td></tr>
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Prab
https://wikimd.org/index.php?title=HER2&diff=5245462&oldid=prev
Prab: CSV import
2024-02-23T15:11:14Z
<p>CSV import</p>
<p><b>New page</b></p><div>'''HER2''' or '''Human Epidermal growth factor Receptor 2''' is a protein that in humans is encoded by the ERBB2 gene. HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this gene has been shown to play an important role in the development and progression of certain aggressive types of [[Breast cancer|breast cancer]].<br />
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== Function ==<br />
In normal cells, HER2 controls aspects of cell growth and division. However, when the HER2 gene is mutated, cells can grow and divide in an uncontrolled way, leading to the development of cancer.<br />
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== Role in Cancer ==<br />
HER2 is found in excessive amounts on the surface of some cancer cells, including some types of [[Breast cancer|breast cancer]], [[Ovarian cancer|ovarian cancer]], [[Stomach cancer|stomach cancer]], and other solid tumors. These cancers are often referred to as "HER2-positive" and they tend to be more aggressive than other types of cancer.<br />
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== HER2 Testing ==<br />
[[HER2 testing]] is used to determine if a breast cancer is HER2-positive. This is important because HER2-positive breast cancers can be treated with drugs that specifically target the HER2 protein, such as [[Trastuzumab|trastuzumab]] and [[Pertuzumab|pertuzumab]].<br />
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== Treatment ==<br />
HER2-positive cancers are typically treated with a combination of surgery, radiation therapy, and chemotherapy. In addition, targeted therapies that specifically attack the HER2 protein, such as [[Trastuzumab|trastuzumab]] and [[Pertuzumab|pertuzumab]], are often used.<br />
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== See Also ==<br />
* [[Breast cancer]]<br />
* [[Ovarian cancer]]<br />
* [[Stomach cancer]]<br />
* [[HER2 testing]]<br />
* [[Trastuzumab]]<br />
* [[Pertuzumab]]<br />
<br />
[[Category:Oncology]]<br />
[[Category:Breast cancer]]<br />
[[Category:Ovarian cancer]]<br />
[[Category:Stomach cancer]]<br />
[[Category:HER2 testing]]<br />
[[Category:Trastuzumab]]<br />
[[Category:Pertuzumab]]<br />
<br />
{{stub}}</div>
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