https://wikimd.org/index.php?action=history&feed=atom&title=HDAC7 2026-04-25T09:06:20Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=HDAC7&diff=5378064&oldid=prev 2024-03-09T21:20:47Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;HDAC7&#039;&#039;&#039; or &#039;&#039;&#039;Histone Deacetylase 7&#039;&#039;&#039; is a [[enzyme|enzyme]] that in humans is encoded by the HDAC7 [[gene|gene]]. It is a member of the [[histone deacetylase]] family, which is involved in a multitude of cellular processes, such as [[cell cycle|cell cycle progression]], [[cell differentiation|cell differentiation]], and [[apoptosis|apoptosis]].<br /> <br /> == Function ==<br /> HDAC7 is a [[histone deacetylase]] (HDAC) that acts on [[chromatin]] to regulate [[gene expression]]. It is part of the [[Class II histone deacetylases|Class II]] HDAC family, which are primarily located in the [[cell nucleus|nucleus]] and are involved in the regulation of numerous cellular processes. HDAC7, like other members of the HDAC family, removes [[acetyl]] groups from [[histone]] proteins, which leads to the condensation of chromatin and suppression of gene expression.<br /> <br /> == Clinical Significance ==<br /> Alterations in the function or expression of HDAC7 have been linked to several human diseases, including [[cancer]], [[neurodegenerative diseases]], and [[cardiovascular diseases]]. In cancer, overexpression of HDAC7 has been observed in several types of tumors, suggesting a potential role in [[tumorigenesis]]. In neurodegenerative diseases, HDAC7 has been implicated in the regulation of [[neuronal death]], and in cardiovascular diseases, it has been associated with the regulation of [[endothelial cell]] function and [[vascular remodeling]].<br /> <br /> == Research ==<br /> Research into HDAC7 is ongoing, with studies focusing on its role in disease processes and its potential as a therapeutic target. Inhibitors of HDAC7 are being investigated for their potential use in the treatment of various diseases, including cancer and neurodegenerative diseases.<br /> <br /> == See Also ==<br /> * [[Histone deacetylase]]<br /> * [[Histone deacetylase inhibitor]]<br /> * [[Epigenetics]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Enzymes]]<br /> [[Category:Genes]]<br /> [[Category:Epigenetics]]<br /> [[Category:Cell biology]]<br /> [[Category:Medical genetics]]<br /> <br /> {{medicine-stub}}</div>

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