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Guaiacol - Revision history
2026-04-27T00:11:36Z
Revision history for this page on the wiki
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https://wikimd.org/index.php?title=Guaiacol&diff=6528576&oldid=prev
Prab at 17:28, 18 March 2025
2025-03-18T17:28:35Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:28, 18 March 2025</td>
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Prab
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Prab: CSV import
2025-03-17T12:20:45Z
<p>CSV import</p>
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Prab: CSV import
2025-02-10T18:50:20Z
<p>CSV import</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:50, 10 February 2025</td>
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Prab
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Prab: CSV import
2024-02-23T14:59:37Z
<p>CSV import</p>
<p><b>New page</b></p><div>'''Guaiacol''' is a naturally occurring organic compound with the formula C6H4(OH)(OCH3). Although it is biosynthesized by a variety of organisms, this yellowish aromatic oil is usually derived from guaiacum or wood creosote. Samples darken upon exposure to air and light. Guaiacol is present in wood smoke, resulting from the pyrolysis of lignin. The compound contributes to the flavor of many substances such as whisky and roasted coffee.<br />
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==Chemical Properties==<br />
Guaiacol is a derivative of phenol with a methoxy group in the ortho position. It is a slightly yellow crystalline solid with a strong, penetrating odor. It is soluble in water and common organic solvents. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes to form a variety of products.<br />
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==Uses==<br />
Guaiacol is used in the synthesis of other organic compounds such as vanillin. It is also used as an expectorant, an antiseptic, and a local anesthetic. Guaiacol is also used in the preparation of synthetic flavors and in perfumery.<br />
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==Health Effects==<br />
Exposure to guaiacol can cause irritation to the skin, eyes, and respiratory tract. Ingestion can lead to symptoms such as nausea, vomiting, and abdominal pain. Long-term exposure can lead to more serious health effects such as liver and kidney damage.<br />
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==See Also==<br />
* [[Phenol]]<br />
* [[Vanillin]]<br />
* [[Wood creosote]]<br />
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[[Category:Organic compounds]]<br />
[[Category:Phenols]]<br />
[[Category:Flavors]]<br />
[[Category:Perfumery]]<br />
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