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	<title>Goldman equation - Revision history</title>
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	<updated>2026-04-26T22:38:49Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=Goldman_equation&amp;diff=6533446&amp;oldid=prev</id>
		<title>Prab at 17:13, 22 March 2025</title>
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		<updated>2025-03-22T17:13:20Z</updated>

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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
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	<entry>
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		<title>Prab: CSV import</title>
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		<updated>2025-03-17T13:42:34Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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		<author><name>Prab</name></author>
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		<updated>2025-02-10T18:39:35Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Goldman_equation&amp;diff=5243689&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Goldman_equation&amp;diff=5243689&amp;oldid=prev"/>
		<updated>2024-02-23T13:41:12Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Goldman equation&amp;#039;&amp;#039;&amp;#039; is a fundamental concept in [[physiology]] and [[biophysics]], particularly in the study of [[cell membrane]]s. It is named after the American physiologist [[David E. Goldman]] who first proposed the equation in 1943.&lt;br /&gt;
&lt;br /&gt;
== Overview ==&lt;br /&gt;
The Goldman equation calculates the [[membrane potential]] that results from multiple ions. It is an extension of the [[Nernst equation]] which calculates the membrane potential of a single ion. The Goldman equation takes into account the relative permeability of the membrane to different ions, as well as their concentrations on either side of the membrane.&lt;br /&gt;
&lt;br /&gt;
== Mathematical Formulation ==&lt;br /&gt;
The Goldman equation is usually written as follows:&lt;br /&gt;
&lt;br /&gt;
V = RT/F * ln((P_K[K+]_o + P_Na[Na+]_o + P_Cl[Cl-]_i) / (P_K[K+]_i + P_Na[Na+]_i + P_Cl[Cl-]_o))&lt;br /&gt;
&lt;br /&gt;
Where:&lt;br /&gt;
* V is the membrane potential&lt;br /&gt;
* R is the universal gas constant&lt;br /&gt;
* T is the absolute temperature&lt;br /&gt;
* F is Faraday&amp;#039;s constant&lt;br /&gt;
* P_K, P_Na, and P_Cl are the relative permeabilities of potassium, sodium, and chloride ions, respectively&lt;br /&gt;
* [K+]_o, [Na+]_o, and [Cl-]_o are the concentrations of potassium, sodium, and chloride ions outside the cell, respectively&lt;br /&gt;
* [K+]_i, [Na+]_i, and [Cl-]_i are the concentrations of potassium, sodium, and chloride ions inside the cell, respectively&lt;br /&gt;
&lt;br /&gt;
== Applications ==&lt;br /&gt;
The Goldman equation is used in many areas of physiology and biophysics, including:&lt;br /&gt;
* Understanding the resting membrane potential of cells&lt;br /&gt;
* Predicting changes in membrane potential due to changes in ion concentrations or permeabilities&lt;br /&gt;
* Studying the effects of ion channel mutations on membrane potential&lt;br /&gt;
&lt;br /&gt;
== See Also ==&lt;br /&gt;
* [[Nernst equation]]&lt;br /&gt;
* [[Hodgkin-Huxley model]]&lt;br /&gt;
* [[Resting potential]]&lt;br /&gt;
* [[Action potential]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Physiology]]&lt;br /&gt;
[[Category:Biophysics]]&lt;br /&gt;
[[Category:Cell biology]]&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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