https://wikimd.org/index.php?action=history&feed=atom&title=GLI2 GLI2 - Revision history 2026-04-25T09:57:25Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=GLI2&diff=6507595&oldid=prev Prab: CSV import 2025-03-17T13:14:25Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:14, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=GLI2&diff=6236209&oldid=prev Prab: CSV import 2025-02-10T17:53:48Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:53, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Genes on human chromosome 2}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Genes on human chromosome 2}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=GLI2&diff=5299781&oldid=prev Prab: CSV import 2024-02-25T22:09:10Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;GLI2&#039;&#039;&#039; is a [[protein]] that in humans is encoded by the &#039;&#039;GLI2&#039;&#039; [[gene]]. It is a member of the [[GLI-Kruppel]] family of [[zinc finger]] proteins. This protein is a transcription factor that acts as a mediator of [[Sonic hedgehog]] (Shh) signaling, a pathway that regulates body patterning and differentiation during embryogenesis.<br /> <br /> == Function ==<br /> The &#039;&#039;GLI2&#039;&#039; gene encodes a protein that belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized by the presence of three zinc-finger domains in the C-terminal region of the protein. They function as transcription factors which convert Shh signal into transcriptional output in embryonic tissues. Mutations in this gene have been associated with several diseases, including [[Greig cephalopolysyndactyly syndrome]], [[Pallister-Hall syndrome]], [[preaxial polydactyly type IV]], and [[postaxial polydactyly types A1 and B]].<br /> <br /> == Clinical significance ==<br /> Mutations in the &#039;&#039;GLI2&#039;&#039; gene are associated with several human diseases. For example, loss-of-function mutations cause holoprosencephaly, a disorder in which the developing forebrain fails to correctly separate into two hemispheres. On the other hand, gain-of-function mutations in &#039;&#039;GLI2&#039;&#039; are associated with Culler-Jones syndrome, a condition characterized by physical abnormalities including a distinctive facial appearance, intellectual disability, and various health problems.<br /> <br /> == See also ==<br /> * [[GLI1]]<br /> * [[GLI3]]<br /> * [[Sonic hedgehog]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> == External links ==<br /> * [https://www.ncbi.nlm.nih.gov/gene/2736 GLI2] at the [[National Center for Biotechnology Information]]<br /> <br /> [[Category:Transcription factors]]<br /> [[Category:Zinc finger proteins]]<br /> [[Category:Human proteins]]<br /> [[Category:Genes on human chromosome 2]]<br /> <br /> {{Transcription factors}}<br /> {{Zinc finger proteins}}<br /> {{Human proteins}}<br /> {{Genes on human chromosome 2}}<br /> {{stub}}</div> Prab