https://wikimd.com/index.php?action=history&feed=atom&title=GJD3 GJD3 - Revision history 2026-04-21T05:48:01Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=GJD3&diff=6507863&oldid=prev Prab: CSV import 2025-03-17T13:22:18Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:22, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; 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font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=GJD3&diff=5378421&oldid=prev Prab: CSV import 2024-03-09T21:49:23Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;GJD3&#039;&#039;&#039; or &#039;&#039;&#039;Gap Junction Protein, Delta 3&#039;&#039;&#039;, also known as &#039;&#039;&#039;Connexin 31.9&#039;&#039;&#039; or &#039;&#039;&#039;Cx31.9&#039;&#039;&#039;, is a protein that in humans is encoded by the GJD3 gene. It is a member of the [[connexin]] family of proteins, which play a crucial role in the formation of [[gap junction]]s.<br /> <br /> == Function ==<br /> GJD3 is a [[protein]] that is a member of the connexin family. Connexins are integral membrane proteins that form [[gap junction]]s, providing a pathway for the diffusion of low molecular weight materials from cell to cell. Gap junctions are essential for many physiological processes, such as the coordinated depolarization of cardiac muscle, smooth muscle contraction, and the propagation of action potentials in neurons.<br /> <br /> == Structure ==<br /> The GJD3 protein is composed of four transmembrane domains, two extracellular loops, a cytoplasmic loop, and cytoplasmic N- and C-termini. The extracellular loops are responsible for connexin-connexin interactions, while the cytoplasmic loop and N- and C-termini are involved in the regulation of channel gating and connexin trafficking.<br /> <br /> == Clinical significance ==<br /> Mutations in the GJD3 gene have been associated with a variety of diseases, including [[skin disease]]s and [[hearing loss]]. Further research is needed to fully understand the role of GJD3 in these conditions.<br /> <br /> == See also ==<br /> * [[Connexin]]<br /> * [[Gap junction]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> == External links ==<br /> * [https://www.ncbi.nlm.nih.gov/gene/219770 NCBI Gene]<br /> * [https://www.uniprot.org/uniprot/Q8NFK1 UniProt]<br /> <br /> [[Category:Human proteins]]<br /> [[Category:Membrane proteins]]<br /> [[Category:Connexins]]<br /> {{protein-stub}}<br /> {{medicine-stub}}</div> Prab