https://wikimd.com/index.php?action=history&feed=atom&title=GDF2 GDF2 - Revision history 2026-04-07T05:44:28Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=GDF2&diff=6508023&oldid=prev Prab: CSV import 2025-03-17T13:27:00Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:27, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l30">Line 30:</td> <td colspan="2" class="diff-lineno">Line 30:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=GDF2&diff=6236372&oldid=prev Prab: CSV import 2025-02-10T17:56:29Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:56, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=GDF2&diff=5381610&oldid=prev Prab: CSV import 2024-03-10T13:00:25Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;GDF2&#039;&#039;&#039; (Growth Differentiation Factor 2), also known as &#039;&#039;&#039;BMP9&#039;&#039;&#039; (Bone Morphogenetic Protein 9), is a protein that in humans is encoded by the GDF2 gene. It is a member of the [[bone morphogenetic protein]] (BMP) family and the [[TGF-beta superfamily]]. The proteins of this superfamily are highly diverse in function and play crucial roles in a variety of biological processes, including [[cell growth]], [[differentiation]], [[morphogenesis]], [[development]] and [[immune response]].<br /> <br /> == Function ==<br /> GDF2 is a secreted ligand of the [[TGF-beta]] (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of [[SMAD family]] transcription factors that regulate gene expression. GDF2 is involved in the regulation of [[endothelial cell]] function. It also plays a crucial role in maintaining [[vascular integrity]].<br /> <br /> == Clinical significance ==<br /> Mutations in the GDF2 gene have been associated with [[pulmonary arterial hypertension]]. GDF2 is also being studied for its potential role in the treatment of [[liver fibrosis]] and [[cancer]].<br /> <br /> == Structure ==<br /> The GDF2 protein is synthesized as a large precursor molecule, which is cleaved to release the mature protein. The mature GDF2 protein is a dimer, composed of two identical subunits that are linked by [[disulfide bond]]s.<br /> <br /> == Expression ==<br /> GDF2 is expressed in a variety of tissues, including the [[liver]], [[lung]], and [[heart]]. Its expression is regulated by various factors, including [[hypoxia]] and [[inflammatory cytokines]].<br /> <br /> == See also ==<br /> * [[Bone morphogenetic protein]]<br /> * [[TGF-beta superfamily]]<br /> * [[SMAD family]]<br /> * [[Pulmonary arterial hypertension]]<br /> * [[Liver fibrosis]]<br /> * [[Cancer]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Growth factors]]<br /> [[Category:TGF-beta superfamily]]<br /> [[Category:Human proteins]]<br /> <br /> {{medicine-stub}}</div> Prab