https://wikimd.org/index.php?action=history&feed=atom&title=GDF11 GDF11 - Revision history 2026-05-12T23:32:23Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=GDF11&diff=6507523&oldid=prev Prab: CSV import 2025-03-17T13:11:52Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:11, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=GDF11&diff=6237189&oldid=prev Prab: CSV import 2025-02-10T18:09:46Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:09, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{protein-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{protein-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=GDF11&diff=5381370&oldid=prev Prab: CSV import 2024-03-10T12:41:29Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;GDF11&#039;&#039;&#039; or &#039;&#039;&#039;Growth Differentiation Factor 11&#039;&#039;&#039; is a [[protein]] that in humans is encoded by the GDF11 [[gene]]. It belongs to the [[Transforming growth factor beta|TGF-beta]] superfamily of proteins. <br /> <br /> == Function ==<br /> GDF11 is a highly conserved [[regulatory protein]], which means it controls the activity of other genes. It plays a crucial role in [[embryonic development]], including the development of the [[anterior/posterior]] patterning of the [[vertebrate]] [[skeleton]], [[organogenesis]], and [[neurogenesis]]. It is also involved in the regulation of [[aging]] and [[age-related diseases]].<br /> <br /> == Structure ==<br /> The GDF11 protein is a [[dimer]], which means it is composed of two identical subunits. Each subunit is made up of a chain of [[amino acids]]. The protein is synthesized as a precursor molecule that is subsequently cleaved to form the mature protein.<br /> <br /> == Role in Aging ==<br /> Recent studies have suggested that GDF11 levels decline with age and that restoring GDF11 levels in aged mice can reverse some signs of aging, including [[cardiac hypertrophy]] and [[neurodegeneration]]. However, these findings are controversial and further research is needed to confirm these results and to understand the mechanisms involved.<br /> <br /> == Clinical Significance ==<br /> Alterations in the function of GDF11 have been implicated in a variety of diseases, including [[cancer]], [[cardiovascular disease]], and [[neurodegenerative diseases]]. Therefore, GDF11 is a potential target for therapeutic interventions in these diseases.<br /> <br /> == See Also ==<br /> * [[Growth differentiation factor]]<br /> * [[TGF beta signaling pathway]]<br /> * [[Aging]]<br /> * [[Regenerative medicine]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Growth factors]]<br /> [[Category:TGF-beta domain]]<br /> [[Category:Human proteins]]<br /> [[Category:Genes on human chromosome 12]]<br /> {{protein-stub}}<br /> {{medicine-stub}}</div> Prab