https://wikimd.org/index.php?action=history&feed=atom&title=GDF10 2026-05-12T21:33:50Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=GDF10&diff=6507691&oldid=prev 2025-03-17T13:17:46Z

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Prab https://wikimd.org/index.php?title=GDF10&diff=5381321&oldid=prev 2024-03-10T12:37:54Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;GDF10&#039;&#039;&#039; or &#039;&#039;&#039;Growth Differentiation Factor 10&#039;&#039;&#039; is a protein that in humans is encoded by the GDF10 gene. It is a member of the [[Bone Morphogenetic Protein]] (BMP) family and the [[TGF-beta]] superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues.<br /> <br /> == Function ==<br /> GDF10 is a secreted protein that acts as a [[cytokine]] and plays a role in different biological processes including cell growth, [[apoptosis]], and [[cell differentiation]]. It is known to be involved in the development of the nervous system and the maintenance of the adult nervous system. Recent studies have shown that GDF10 plays a significant role in [[neurogenesis]] and [[neuroplasticity]], particularly after [[stroke]] or other types of brain injury.<br /> <br /> == Clinical Significance ==<br /> GDF10 has been implicated in several diseases and conditions. It has been found to be downregulated in [[glioblastoma]], a type of brain cancer, suggesting a potential role in tumor suppression. In contrast, overexpression of GDF10 has been associated with [[osteoarthritis]], indicating a possible role in joint degeneration. <br /> <br /> In the context of stroke recovery, GDF10 has been found to promote neuroplasticity and functional recovery. This has led to the exploration of GDF10 as a potential therapeutic target for enhancing recovery after stroke or other types of brain injury.<br /> <br /> == See Also ==<br /> * [[Bone Morphogenetic Protein]]<br /> * [[TGF-beta]]<br /> * [[Neurogenesis]]<br /> * [[Stroke]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Growth factors]]<br /> [[Category:Cytokines]]<br /> [[Category:Neuroscience]]<br /> [[Category:Medicine]]<br /> <br /> {{medicine-stub}}</div>

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