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Freund's adjuvant - Revision history
2026-04-27T04:07:02Z
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<p><b>New page</b></p><div>'''Freund's adjuvant''' is a solution of [[mineral oil]] and [[emulsifier]], often supplemented with killed [[Mycobacterium tuberculosis]] bacteria. It is named after [[Jules T. Freund]], who developed the substance in 1942. Freund's adjuvant is used in [[vaccine]] production to enhance the [[immune response]] and increase the effectiveness of the vaccine.<br />
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== History ==<br />
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Freund's adjuvant was developed by Jules T. Freund in 1942. Freund was a Hungarian-born American [[immunologist]] who made significant contributions to the field of [[immunology]] and [[vaccine]] development.<br />
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== Composition ==<br />
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Freund's adjuvant is composed of mineral oil and an emulsifier, often supplemented with killed Mycobacterium tuberculosis bacteria. The mineral oil component helps to slow the release of the [[antigen]], prolonging the immune response. The emulsifier helps to create a stable [[emulsion]] of the oil and water-based components of the vaccine. The addition of killed Mycobacterium tuberculosis bacteria helps to further stimulate the immune response.<br />
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== Use in Vaccine Production ==<br />
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Freund's adjuvant is used in vaccine production to enhance the immune response to the antigen. By slowing the release of the antigen and stimulating a stronger immune response, Freund's adjuvant increases the effectiveness of the vaccine.<br />
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== Safety and Side Effects ==<br />
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While Freund's adjuvant is effective at enhancing the immune response, it can also cause side effects. These can include [[inflammation]] at the injection site, [[fever]], and [[lymph node]] enlargement. Because of these side effects, Freund's adjuvant is not typically used in human vaccines.<br />
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== See Also ==<br />
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* [[Adjuvant]]<br />
* [[Vaccine]]<br />
* [[Immunology]]<br />
* [[Jules T. Freund]]<br />
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[[Category:Immunology]]<br />
[[Category:Vaccines]]<br />
[[Category:Medical Terms]]<br />
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