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Flavin adenine dinucleotide - Revision history
2026-04-29T21:40:36Z
Revision history for this page on the wiki
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https://wikimd.org/index.php?title=Flavin_adenine_dinucleotide&diff=6326527&oldid=prev
Prab: CSV import
2025-02-18T12:11:27Z
<p>CSV import</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:11, 18 February 2025</td>
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Prab
https://wikimd.org/index.php?title=Flavin_adenine_dinucleotide&diff=5232529&oldid=prev
Prab: CSV import
2024-02-23T04:31:20Z
<p>CSV import</p>
<p><b>New page</b></p><div>'''Flavin adenine dinucleotide''' (FAD) is a [[redox]] cofactor involved in several important [[metabolism|metabolic reactions]]. It is a molecule that is synthesized from [[riboflavin]] (vitamin B2) and [[adenosine triphosphate]] (ATP).<br />
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== Structure ==<br />
FAD consists of two major portions: the [[adenine]] and [[flavin]] moieties. The adenine portion is composed of a nitrogenous base attached to a five-carbon sugar, ribose, which is further connected to a chain of three phosphate groups. The flavin portion is a ring structure known as isoalloxazine, which is attached to the ribityl part of the molecule.<br />
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== Function ==<br />
FAD is a crucial component in [[oxidation-reduction]] reactions. It acts as a hydrogen acceptor in dehydrogenation reactions, becoming reduced to FADH2. This reduced form can then donate these hydrogen atoms in subsequent reactions, returning to its oxidized state.<br />
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== Role in Metabolic Pathways ==<br />
FAD is involved in several metabolic pathways, including:<br />
* [[Krebs cycle]]: FAD is a key player in the Krebs cycle, where it is reduced to FADH2 in the succinate dehydrogenase reaction.<br />
* [[Beta oxidation]]: In the process of beta oxidation, FAD is reduced to FADH2 during the oxidation of fatty acids.<br />
* [[Electron transport chain]]: FADH2 donates its electrons to the electron transport chain, contributing to the production of ATP.<br />
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== Deficiency ==<br />
A deficiency in FAD can lead to a variety of health problems, including [[dermatitis]], [[glossitis]], and neurological symptoms. This is often due to a deficiency in dietary riboflavin, as the body cannot synthesize FAD without this vitamin.<br />
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== See Also ==<br />
* [[Riboflavin]]<br />
* [[Adenosine triphosphate]]<br />
* [[Metabolism]]<br />
* [[Krebs cycle]]<br />
* [[Beta oxidation]]<br />
* [[Electron transport chain]]<br />
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[[Category:Biochemistry]]<br />
[[Category:Metabolism]]<br />
[[Category:Vitamins]]<br />
[[Category:Cofactors]]<br />
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{{stub}}</div>
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